| Objective:To analyze the clinicopathological characteristics of lung cancer in Yanbian area in the past 15 years to provide a reference for the prevention and treatment of lung cancer in this area.Methods:Collecting 1344 cases of primary lung cancer diagnosed pathologically in the Affiliated Hospital of Yanbian University from January 2006 to December 2020.The times were divided into three periods:2006-2010,2011-2015 and 2016-2020 according to the period of every five years.According to the age at the time of initial diagnosis,the cases were divided into<40 years old group(youth lung cancer group),40-49 years old group,50-59 years old group,60-69 years old group and≥70 years old group.These clinical data were analyze that the age of onset,pathological type,and lesion location of Korean-chinese and Han nationalities patients with lung cancer in three different periods,and to analyze the clinicopathological characteristics of lung cancer between two ethnic groups and different genders at different periods.Results:1.The age of onset of lung cancer:The average ages of onset of the Korean-chinese in the three different periods of time were 63.2,63.8,and64.3,respectively,and the Han were 60.7,61.0,and 62.3,respectively.The average age of onset was gradually increasing,and the average age of onset of the Korean-chinese was higher than that of the Han.The average age of onset between the Korean-chinese and Han nationalities from 2011 to 2015and 2016 to 2020 was statistically different(both P<0.05);The peak ages of onset of the two ethnic groups were the same,both in the 60-69 years group;The number of cases of lung cancer among ethnic youth was increasing year by year.2.The pathological types of lung cancer:The pathological types of lung cancer were mainly adenocarcinoma(45.18%and 46.05%),with no statistical difference(x~2=0.099,P>0.05);There was also statistical difference in the Korean-chinese and Han nationalities on the constituent ratio of squamous cell carcinoma,small cell carcinoma and other types(all P>0.05).The squamous cell carcinoma was the main type of lung cancer in males of the two nationalities,but the constituent ratio of squamous cell carcinoma gradually decreased(P<0.001),the constituent ratio of adenocarcinoma increased(P<0.001),and the other types did not change significantly(all P>0.001).There was no statistical difference among the two nationalities P>0.05).The adenocarcinoma was the main type of lung cancer in females of the two nationalities,and the constituent ratio of adenocarcinoma gradually increased(P<0.001),while the constituent ratio of squamous cell carcinoma gradually decreased(P<0.001),and the constituent ratios of other types did not change significantly(all P>0.05);The proportion of adenocarcinoma of female of Korean-chinese nationality was higher than that of Hannationality(85.6%vs 68.9%),there was a statistical difference(P<0.0125);The constituent ratio of squamous cell carcinoma(5.5%vs13.2%)and the constituent ratio of small cell carcinoma(5.0%vs 12.5%)were lower than female of Han nationality,with statistical differences(all P<0.0125).There was no statistical differences in other types(P>0.05).3.The location of lung cancer:The location of lung cancer of Korean-chinese,Han nationalities and different genders was the most common in the upper lobe of the right lung,and the middle lobe of the right lung was the least common.All statistic was no difference(all P>0.05).Conclusion:1.The peak age of onset of lung cancer in the Korean-chinese and Han nationalities in Yanbian area was 60-69 years old,and the average age of onset of lung cancer of Korean-chinese nationality was higher than that of Han nationality.2.The adenocarcinoma in females of Korean-chinese and Han nationalities was main pathological type of lung cancer,but the constituent ratio of adenocarcinoma of female in Korean-chinese nationality was higher than that in Han nationality,while the proportion of squamous cell carcinoma and small cell carcinoma was lower than that in Han nationality.3.Squamous cell carcinoma was main pathological type for male of Korean-chinese and Han nationalities,and its constituent ratio was gradually decreasing.The constituent ratio of adenocarcinoma was increasing.There was no significant difference between the two nationalities.4.The most common location of lung cancer was the upper lobe of the right lung,the least was the middle lobe of the right lung in Korean-chinese,Han nationalities and different genders. |
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