| ObjectiveBased on the standard service path under the family pharmacist system,home-based pharmaceutical care for patients with type 2 diabetes was conducted,and the intervention effect of home-based pharmaceutical care service on type 2 diabetic patients was evaluated mainly from three aspects:treatment compliance,safety and effectiveness,to provide reference and basis for family pharmacists to carry out and further improve the management of home medication for chronic diseases including type 2 diabetes.MethodsTaken the Nanhai District family pharmacist Smart Workstation and the Endocrinology Department of our hospital as the research site,screened patients diagnosed with type 2 diabetes between January 2020 and December 2020 as the research objects,a randomized controlled trial was designed,and the research objects were randomly selected and divided into observation group and control group by using the random number table.The control group received routine medical care management,while the observation group received individualized home-based pharmaceutical care and regular follow-up services provided by family pharmacists.Compared the differences between subjective evaluation indexes(treatment compliance and medication deviation)and objective evaluation indexes(drug adverse events and disease control)before and after intervention and between groups,so as to evaluate the compliance,safety and effectiveness of home-based pharmaceutical care.ResultsA total of 77 patients with type 2 diabetes were enrolled in this study,and a total of 6 cases were dropped during the observation period.In the end,a total of 71 subjects completed the observation study,including 34 cases in the observation group and 37 cases in the control group.1.Basic information:The two groups of patients were balanced and comparable in terms of gender,age,number of medications,duration of disease,complications,and comorbidities(P>0.05).2.Treatment compliance:After different management interventions,the total scores of treatment compliance and the scores of various dimensions of the two groups of patients were improved.①Total score:The two groups are comparable before the intervention(P>0.05),there are significant differences between the two groups before and after the intervention(P>0.05),and there are significant differences in the total score and the difference between the groups after the intervention(P<0.05);②Compliance with taking medicine and doctor:The scores of the two groups before the intervention may be compared(P>0.05),and only the two dimensions of scores of the observe group is obvious after intervention(P<0.05),and the scores are significant differences between the two groups after the intervention;③Diet Control and Sports Compliance:The scores of the two groups before intervention is not comparable(P<0.05),and the difference between the two groups before and after the intervention is obvious(P<0.05);④Blood glucose monitoring compliance:The two groups are comparable before the intervention(P>0.05),there are significant differences between the two groups before and after the intervention(P<0.05),and there are significant differences in the total score and the difference between the groups after the intervention(P<0.05).3.Medication deviation:There was no significant difference in medication deviation between the two groups before intervention(P>0.05).After intervention,medication deviation in the observation group was significantly improved compared with the control group,and there was significant difference(P<0.05).4.Safety:The total number of adverse events occurred in both groups was 9,and the incidence of adverse events was 26.47%and 24.32%,respectively,and there was no statistically significant difference(P>0.05).5.Effectiveness:①Glucose-related indicators:There were no significant differences in FPG，2hPG,HbA1c and the criteria between groups before intervention(P>0.05).After intervention,the levels and the compliance rate of FPG,2HPG and HbAlc in the two groups were significantly improved compared with before intervention,but the number of monitored cases of HbAlc decreased significantly.The levels of all indicators and the compliance rate of the observation group before and after intervention showed significant differences(P<0.05),while only the compliance rate of HbAlc in the control group after intervention showed significant differences compared with before intervention(P<0.05).After intervention,the levels of FPG,2HPG and HbAlc and the compliance rate of 2HPG and HbAlc between the two groups were significantly different(P<0.05).②Comprehensive indicator:Before intervention,the number of cases of comprehensive index monitoring in the observation group and the control group was 32,and the number of cases reaching the standard was 2 and 1,respectively.There was no significant difference in monitoring compliance and compliance rate between groups(P>0.05).After intervention,the number of monitoring cases in the two groups was 18 cases and 10 cases,respectively.There was significant difference in monitoring compliance between the two groups(P<0.05),but the comprehensive monitoring indicators did not reach the standard.ConclusionThrough the observation of this study,on the basis of routine medical care management,providing individualized home-based pharmaceutical care and follow-up services for patients with type 2 diabetes can significantly improve patients’ medication behavior compliance,compliance behavior compliance,diet control and exercise behavior compliance,and blood glucose monitoring behavioral compliance,reduce the occurrence of medication deviation,and further improve the patient’s disease control situation.Therefore,the development of home-based pharmaceutical care has important and positive significance in ensuring patients’ treatment compliance and effectiveness. |
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