Discussion On The Medication Rule Of Professor Li Li In The Treatment Of Vertigo Based On Data Mining

Objective: To collect Professor Li Li ’s prescriptions for Chinese medicine for dizziness,and use data mining techniques to analyze the frequency of the drug,cluster analysis,factor analysis,and analyze and refine the distinguishing features of Professor Li Li ’s treatment of dizziness and the prescriptions.The style is carried out,summarizing the dialectical thinking and medication experience of Professor Li Li in treating dizziness,highlighting the advantages of Chinese medicine in treating dizziness,improving the clinical cure rate of patients,and improving the quality of life of patients.Method:1.Strictly follow the inclusion and exclusion criteria for vertigo,and collect the first Chinese medicine prescriptions from 2000 to 2010 that were treated in the outpatient department and ward of the Department of Encephalology of Henan Provincial Hospital of Traditional Chinese Medicine and were treated by Professor Li Li.2.After standardized preprocessing of Chinese medicine prescription data,enter Epi Data3.1 to establish an electronic database.3.Use SPSS22.0 statistical software and data mining technology for statistical analysis.4.Combined with statistical results,analyze and discuss Professor Li Li’s experience in treating vertigo.Results:1.Basic information: Of the 263 cases of vertigo collected this time,126 were female patients,accounting for 47.91%,and 137 were male patients,accounting for52.09%.The minimum age is 18 years,the maximum age is 85 years,and the average age is 50.31±15.87 years.2.Frequency analysis: A total of 263 prescriptions were collected in this study,involving 122 types of drugs.Drugs with a frequency of ≥10% werehigh-frequency drugs.A total of 47 flavors were recorded.The cumulative frequency was 3692 times,accounting for 84.47% of the total frequency.tangerine peel,Poria cocos,Pinellia ternata,Fructus Crataegi,Radish seed,liquorice,gastrodia elata,Forsythia suspense,Chrysanthemum,Medicated Leaven,Fructus Viticis,Ligusticum wallichii,Angelica sinensis,earthworm,uncaria,Macroradixix Paeoniae Rhoma,Dan-Shen Root,Concha Haliotidis,rhizoma alismatis,malt,Radix Achyranthis Bidentatae,ginseng,Paeoniae Radix Alba,Dragonsbones,plant mainly,Radix Scutellariae,ginger,oyster,selfheal,Endothelium corneum,olivercommiocorps,shameless,Fructus Gardeniae,Aurantii fructus immaturus,parasitic loranthus,Schisandra chinensis,Semen Ziziphi Spinosae,Flos Carthami,peach seed,Plantain Seed,Caulis Spatholobi,Polygni Mu ltiflori Caulis,Pericarpium Citri Reticulatae Viride.(1)Distribution of high-frequency Chinese medicine properties: 12 categories are involved,and the frequency(frequency)of each drug category can be divided into tonic medicine 14.79%(546 times),digestive medicine 13.87%(512 times),and flat liver Extinguishing wind 13.52%(499 times),activating blood circulation and removing blood stasis medicine 10.43%(385 times),antihypertensive medicine10.27%(379 times),heat-clearing medicine 9.80%(362 times),diuretic hydration8.34%(308 times),qi 7.56%(279 times)of medicine,6.45%(238 times)of phlegm,cough and asthma,3.11%(115 times)of antipsychotic,0.95%(35 times)of rheumatism,0.92%(34 times)of astringent medicine.(2)Four-frequency distribution of high-frequency drugs: 15 flavors of warm medicines,a total of 1297 times,accounting for 35.13%,17 flavors of cold medicines,a total of 1201 times,accounting for 32.53%,13 flavors of flat medicines,a total of 1015 times,accounting for 31.85 %,Cooling medicine 2 flavors,a total of179 times,accounting for 4.85%.(3)Distribution of five flavors of high-frequency drugs: 27 flavors of sweet medicine,a total of 2096 times,accounting for 52.90%,16 flavors of spicy medicine,a total of 1497 times,accounting for 37.78%,20 flavors of bitter medicine,a total of14,12 times,accounting for 35.64%,sour medicine 6 flavors,a total of 360 times,accounting for 9.09%,3 savory medicines,a total of 233 times,accounting for5.88%,1 light flavor medicine,a total of 216 times,accounting for 5.45%,1astringent medicine,a total of 54 times,accounting for 1.36 %.(4)Distribution of high-frequency drugs by menstruation: they are distributed in the twelve meridians.In order of frequency,the top three are 18 flavors of the spleen meridian medicine for a total of 1920 times,accounting for 52.00%,28 flavors of the liver meridian medicine for a total of 1873 times,accounting for50.73%,and 16 flavors of the gastric meridian medicine for a total of 1402 times,accounting for 37.97%.,Followed by lung meridian(34.64%),heart meridian(29.26%),kidney meridian(16.58%),bile meridian(9.40%),bladder meridian(8.88%),small intestine meridian(7.75%),pericardial meridian(7.67%)),Large intestine meridian(3.25%),triple burn meridian(1.08%).3.Cluster analysisSquare group based on cluster analysis:The first category: Dried tangerine peel,Poria cocos,Pinellia ternata,Fructus Crataegi,Radish seed,Forsythia suspense,Medical Leaven;The second category: gastrodia elata,earthworm,uncaria,Concha Haliotidis,Radix Achyranthis Bidentatae,Dragonsbones,Radix Scutellariae,oyster,selfheal,Eucommia ulmoides,Fructus Gardeniae,parasitic loranthus,Plantain Seed;The third category: liquorice,Chrysanthemum,Fructus Viticis,Macrocephalae Rhizoma,rhizoma alismatis,ginger;Fourth category: Ligusticum wallichii,Angelica sinensis,Radix Puerariae,Radix Paeoniae Rubra,Dan-Shen Root;Fifth category: malt,ginseng,Paeoniae Radix Alba,plant mainly,Endothelium corneum,bamboo shavings,scorpio,turmeric,Aurantii fructus immaturus,Schisandra chinensis,Semen Ziziphi Spinosae,Flos Carthami,peach seed,Caulis Spatholobiica,Polygni Citri Reticulatae Viride;4.Factor analysis:Twelve common factors were extracted for the drug combination commonly used by Professor Li Li in this study.Factor 1: Forsythia suspense,Fructus Crataegi,Radish seed,Medicated Leaven;Factor 2: Fructus Gardeniae,Eucommia ulmoides,parasitic loranthus,Radix Scutellariae;Factor 3: uncaria,Concha Haliotidis,earthworm,gastrodia elata;factor 4: Dried tangerine peel,Pinellia ternata,Poria cocos;factor 5: oyster,Dragonsbones,Radix Achyranthis Bidentatae;factor 6:Schisandra chinensis,plant mainly,ginseng;factor 7: Flos Carthami Peach seed;factor 8: Fructus Viticis,Chrysanthemum;factor 9: Pericarpium Citri Reticulatae Viride,turmeric;factor 10: Ligusticum wallichii,Radix Puerariae,Dan-Shen Root,Radix Paeoniae Rubra;factor 11: Caulis Spatholobi,nocturnal vine;Factor 12:Paeoniae Radix Alba,date kernel.in conclusion:1.Based on frequency analysis,Professor Li Li’s clinical medications for dizziness include spleen relieving phlegm,digestion and stomach,Pinggan Xifeng,Huoxue Huayu,Shufeng Qingre.2.The cluster analysis was classified into 5 types of drug combinations,corresponding to Professor Li Li’s basic prescription for treating dizziness,which is mainly for strengthening the spleen and stomach,flattening the liver and burying the sun,relieving wind and clearing heat,nourishing blood,and promoting blood circulation.3.The 12 common factors extracted by factor analysis are commonly used by Professor Li Li for digestion and stomach,expelling wind and clearing heat,spleen yang,relieving phlegm and spleen,promoting blood circulation,improving qi and nourishing yin,and nourishing blood and soothing nerves.,Mostly for the treatment of vertigo-type syndromes,common combination of syndromes.4.Professor Li Li treats vertigo,distinguishes between deficiency and reality,pays attention to the protection of the spleen and stomach,and complements the elimination,so as to map the essence;the medication is used to closely surround the basic pathogenesis of wind,sputum,deficiency,and stasis.Combination and flexible treatment.