Observation Of Clinical Effect By Using Chushi Decoction Combined With IRPL To Treat Spleen Stomach Damp Heat Syndrome MGD Dry Eye

By comparing the clinical efficacy of Chushi Decoction combined with IRPL and IRPL alone to treat spleen stomach damp heat syndrome MGD dry eye,explored the mechanism of action of Dampness-Eliminating Decoction in the treatment of dry eye,providing a new idea for the clinical treatment of spleen and stomach damp-heat typ-e MGD dry eye.Method:A total of 70 patients who met the criteria for inclusion in this study were collected,and70 patients were randomly divided into observation group and control group,with 35 cases in each group.The observation group was given the addition and subtraction of dehumidification decoction combined with IRPL,and polyethyleneglycol eye drops for treatment,while the control group was given only IRPL combined with p-olyethyleneglycol eye drops for 1 course of treatment.By comparing the changes in score of OSDI,meibomian gland secretion status score,meibomian gland secretion trai-t score,TMH,NIBUT,scores of CFS and TCM syndrome score of the two groups o-f patients before and after treatment,and performed statistical analysis on the results.Results:1、A total of 70 patients(140 eyes in total)were collected in this study,and 6 cases(12eyes)fell off,with a drop-out rate of 8.57%.2、Comparison of various indicators before treatment: in terms of gender,age,sco-re of OSDI,meibomian gland secretion status score,meibomian gland secretion trait score,TMH,NIBUT,scores of CFS and TCM syndrome score of the two groups of patients,the statistical analysis results showed that there is no statistically significant d-ifference in the data of various indicators(P>0.05).3、Comparison of various indicators after treatment:(1)After treatment,the meibomian gland secretion status score and meibomian gl-and secretion trait score of the two groups of patients decreased compared with before,and the differences are all significant and statistically significant(average P<0.05).The meibomian gland secretion status score and meibomian gland secretion trait score o-f the observation group decreased better than those of the control group after treatment,and the difference was statistically significant(average P<0.05).(2)After treatment,the TMH of the two groups of patients increased compared with before,and the difference was statistically significant(average P<0.05).The increase of TMH if the observation group after treatment was better than that in the control group,and the difference was statistically significant(P<0.05).(3)After treatment,the NIBUT of the two groups of patients was prolonged com-pared with before,and the difference was statistically significant(average P<0.05).The prolongation of NIBUT in the observation group was better than treatment was better than that in the control group,and the difference was statistically significant(P<0.05).(4)The CFS scores of the two groups of patients decreased after treatment,and t-he difference was statistically significant(average P<0.05).The decrease in CFS scores of the observation group after treatment was better than that of the control group,and the difference was statistically significant(P<0.05).(5)The scores of OSDI of the two groups of patients decreased after treatment,and the difference was statistically significant(all P<0.05).The scores of OSDI of the observation group decreased better than the control group after treatment,and the diff-erence was statistically significant(P<0.05).(6)After treatment,the TCM syndrome scores of the two groups of patients wer-e lower than before,and the difference was statistically significant(all P<0.05).After treatment,the TCM syndrome score of the observation group was lower than that of t-he control group,and the difference was statistically significant(P<0.05)).Conclusion:1.The simple use of IRPL and the addition and subtraction of Chushi Decoction combined with IRPL are effective in the treatment of spleen stomach damp heat syndrome MGD dry eye;2.Compared with the simple use of IRPL,the addition and subtraction of Chushi Decoction combined with IRPL can better improve the function of meibomian glands,promote tear secretion,enhance tear film stability,and reduce ocular surface damage in the treatment of spleen stomach damp heat syndrome MGD dry eye;3.Compared with the simple use of IRPL,the addition and subtraction of Chushi Decoction combined with IRPL can better improve the clinical symptoms of patients and TCM syndromes in the treatment of spleen stomach damp heat syndrome MGD dry eye.