| Objective: To observe the effects of early pulmonary rehabilitation on the pulmonary function,exercise tolerance,respiratory symptoms,quality of life and psychological state in patients with moderate to severe acute exacerbation of chronic obstructive pulmonary disease(AECOPD),and to explore its safety and clinical effects in patients with moderate to severe AECOPD.Methods: 70 patients with moderate to severe AECOPD hospitalized in the department of respiratory and critical care medicine,handan central hospitall from November 2019 to November 2020 were selected and randomly divided into rehabilitation group and control group.Two groups of patients were treated with routine drugs and to maintain daily activities during hospitalization and after discharge.The rehabilitation group patients start pulmonary rehabilitation training within 72 hours after admission and continue 8 weeks after discharge,the content including exercise training,breathing training,row of phlegm training and health education.The lung function(FEV1/FVC,FEV1),exercise tolerance(6MWD),respiratory system symptoms(Cough and Sputum score,m MRC),quality of life(CAT)and psychological state(HAD)were evaluated before intervention and 8 weeks after discharge.Results: After 8 weeks of discharge,the 6MWD,Cough and Sputum score,m MRC score and CAT score were all improved compared with before in both rehabilitation group and control group,and the improvement was more obvious in the rehabilitation group.HAD was changed in the rehabilitation group,but not in the control group.Before and after intervention,there was no significant difference in FEV1/FVC,FEV1 between the two groups.Conclusion: In the early period of hospitalization,it is safe and feasible for moderate to severe AECOPD patients to start pulmonary rehabilitation training.It can improve patients’ exercise tolerance,respiratory symptoms,quality of life and psychological state,but has no significant effect on lung function compared with the control group in a short time. |