Study On The Correlation Between Tubal Inflammatory Infertility And Reproductive Tract Infection And The Distribution Of TCM Syndrome Types

Objective:To investigate the relationship between tubal inflammatory infertility,tubal obstruction and adhesion,and influencing factors,and to study the distribution characteristics of TCM syndromes and related influencing factors of tubal inflammatory infertility.Method:The first part is a case-control study.The observation group chose to undergo hysteroscopic laparoscopic surgery in the gynecological inpatient department of Shanxi Provincial Hospital of Traditional Chinese Medicine from February 2020 to December 2020.A total of 48 cases of tubal inflammatory infertility met the inclusion criteria;control The group chose to stay in the gynecological ward during the same period for infertility caused by endometrial polyps or(and)polycystic ovary syndrome to undergo hysteroscopic laparoscopic surgery.A total of 46 cases of normal fallopian tube appearance were seen during the operation.(1)Instruct patients to fill in the form of previous reproductive tract infections and collect relevant data;(2)Collect the patient’s lower genital tract secretions,use the bacterial culture identification method to detect the patient’s genital tract bacteria,mold,UU,etc.,use the polymerase chain reaction(PCR)method to detect CT,gonorrhoeae;(3)Observe pelvic conditions during hysteroscopy,and score fallopian tube obstruction and pelvic adhesions;(4)Enter the data into an Excel table to establish a database,and use SPSS26.0to process and analyze.The second part is a study on the distribution of syndrome types.The data comes from patients who were admitted to the gynecological ward of Shanxi Provincial Hospital of Traditional Chinese Medicine for "chronic pelvic inflammatory disease and infertility" during hysteroscopy and confirmed tubal inflammatory infertility from 2017 to 2019.187 cases.Use the inpatient department case system to screen eligible cases,enter the relevant information into an Excel table to establish a database based on the content of the case record,and use SPSS 26.0 to process and analyze.Results:(1)The results of the case-control study on tubal inflammatory infertility in this study are as follows:(1)Multivariate logistic analysis found that UU is related to tubal inflammatory infertility(P=0.000,OR =21.489,95%CI [5.500～83.959]),and there is a related relationship between pelvic and abdominal surgery history and tubal inflammatory infertility(P=0.002,OR=6.368,95%CI [1.991-20.375]),both of which are risk factors for tubal inflammatory infertility;CT,NG,BV,VVC,TV,history of induced abortion and tubal inflammatory failure There was no statistically significant difference in pregnancy(P>0.05).(2)Ordinal multi-class logistic regression analysis found that the history of pelvic and abdominal surgery(P=0.014,OR=8.628,95,95%CI[-3.865～-0.445])had a significant impact on the fallopian tube score,but the history of abortion,UU,CT,VVC,TV,and BV have an effect on fallopian tube score(P>0.05).(2)The results of the distribution of the syndrome types of tubal inflammatory infertility in this study are as follows:(1)The qi stagnation and blood stasis type accounted for 21.4%,the damp-heat stasis type accounted for 67.4%,the kidney deficiency and blood stasis type,the phlegm dampness stasis type,and cold blood stasis type.Less,accounting for only 2.1%,2.1%,4.8%,and 1.6%of other syndrome types;(2)History of induced abortion between TCM syndromes(X2=3.892,P=0.565),history of pelvic and abdominal surgery(X2= 1.907,P=0.862),the history of reproductive tract infection(X2=9.699,P=0.084)was not statistically significant.(3)Comparing the course of different TCM syndrome types,the difference is statistically significant(X2=13.444,P=0.020).(4)The age comparison between different TCM syndrome types is statistically significant(X2=22.501,P=0.000).The age of patients with damp-heat stasis type,qi stagnation and blood stasis type,and phlegm-damp stasis type is relatively young,and kidney deficiency Patients with blood stasis type and cold blood stasis type are relatively older.Conclusion:(1)UU and history of pelvic and abdominal surgery are risk factors for tubal inflammatory infertility(OR>1);(2)the history of pelvic and abdominal surgery has a significant impact on the severity of tubal obstruction and adhesion(P<0.05).(3)The distribution of syndromes in patients with tubal inflammatory infertility is most in patients with damp-heat stasis,followed by qi stagnation and blood stasis;(4)Age and length of disease have a certain influence on the distribution of TCM syndromes,history of pelvic and abdominal surgery,The influence of abortion history and pelvic infection history on the distribution of TCM syndromes needs further study.