| Pulmonary arterial hypertension(PAH)is an intractable condition which has progressive debilitating symptoms and poor prognosis.In recent years,with the rapid development of drugs for the treatment of PAH,which have been widely used in patients with PAH,the prognosis of patients with PAH has been significantly improved.However,it is still controversial whether anticoagulant therapy should be used in patients with PAH.And there are no randomized controlled trials and high-quality cohort studies to confirm the efficacy of anticogulantion so far.In addition,the classification of PAH is complex and has many subtypes.And few studies on this disease were conducted in China.To solve the problems mentioned before,this paper first finds out all the research related to the anticoagulant treatment of PAH,and then carries out a meta-analysis to find out whether the anticoagulant treatment should be performed for patients with PAH.Then,we collected the data of patients with PAH in recent years in our hospital,summarized the demographic characteristics and treatment measures of patients with PAH in China,and compared them with those in Europe and America.In the end,we will discuss interaction between anticoagulants and pulmonary vasodilation therapy.According to the analysis,anticoagulation can improve the prognosis of patients with PAH.The main subtype of pulmonary hypertension in China is systemic lupus erythematosus associated with PAH.In addition,there are still some deficiencies in the treatment and cognition of PAH in our country. |