Analysis Of Related Factors Affecting The Degree Of Resection And Postoperative Complications Of Sphenoid Ridge Meningioma

Objective: To explore the clinical factors influencing the degree of surgical resection and postoperative complications of sphenoid ridge meningioma.Methods: The clinical data of 38 patients with sphenoid ridge meningioma who underwent microsurgical treatment in the Second Affiliated Hospital of Nanchang University from January 2017 to August 2020 were retrospectively analyzed.The clinical data of the patients were analyzed by statistical software SPSS22.0 to explore the clinical factors affecting the degree of surgical resection and postoperative complications.Results: Among the 38 patients included,there were 10 males and 28 females with a ratio of 1:2.8,aged 53.9±2.1years old,and the median age was 56 years old.Total resection was performed in 18 patients,with a total resection rate of47.37%,and subtotal resection was performed in 20 patients(52.63%),including 18 Simpson grade I resection,15 Simpson grade II resection,1 Simpson grade III resection,and 3 Simpson grade IV resection.All patients were followed up for 3months to 4 years,and no patients died after surgery.Postoperative complications mainly included 7 cases of rebleeding in the operative area,6 cases of oculomotor nerve palsy,1 case of intracranial infection,1 case of cerebrospinal fluid leakage,1case of postoperative hemiplegia,and 1 case of secondary epilepsy after discharge.Univariate analysis showed that the degree of adhesion,tumor diameter and volume,invasion of cavernous sinus,invasion of internal carotid artery and branches,invasion of optic nerve canal were related to the degree of tumor resection.Preoperative epilepsy,tumor type,total resection,tumor diameter and volume were related to postoperative complications.Multivariate logistic regression analysis showed that adhesion degree was an independent risk factor affecting surgical resection.Conclusion: The goal of surgical resection of sphenoid ridge meningiomas is to completely remove the tumor without preserving nerve function,and total resection of the tumor is not the only criterion to evaluate postoperative resection.For tumors that do not involve cranial nerves and internal carotid artery,we should pursue total resection of the tumor,while for tumors that involve caversous sinus,optic nerve canal and neurovascular adhesion closely,we can use a little residual,supplemented by postoperative radiotherapy,which is of great significance to improve the quality of life of patients after surgery.