To Explore The Effect Of Dialysis Sufficiency On Quality Of Life Of MHD Patients

Objective: To explore the correlation between dialysis adequacy and maintenance hemodialysis(MHD)patients’ quality of life,to provide data and theoretical basis for guiding clinicians to adjust,improve hemodialysis programs,educate patients,and improve the quality of life of patients with MHD.Methods: Sixty-eight MHD patients in our dialysis center were selected.The dialysis age was more than 6 months.Basic information was collected,including gender,age,dialysis age,smoking,drinking history,and primary disease.Biochemical indicators: blood phosphorus(P),blood calcium(Ca),whole parathyroid hormone(i PTH),albumin(ALb),hemoglobin(Hb),and urea nitrogen(BUN).Patients were divided into two groups according to the urea clearance index Kt/V: 38 patients in the adequately dialyzed group(Kt/V≥1.2),30 patients in the insufficiently dialyzed group(Kt/V <1.2),and the two groups were compared with the SF-36 scale In The MOS item short from heath survey(SF-36),the total physical health score(PCS),total mental health score(MCS),and comprehensive score are analyzed.The scores of the two groups are analyzed,and the blood phosphorus,Changes in serum calcium,whole parathyroid hormone,albumin,and hemoglobin were analyzed by statistical methods in two groups of basic data,biochemical indicators,and quality of life scores,and correlation analysis was performed using spearman.Results: 1.In this experiment,68 patients with MHD,38 patients with adequate dialysis,and 30 patients with insufficient dialysis were collected.There was no significant difference in the basic data between the two groups with sufficient dialysis and inadequate dialysis(P> 0.05).Including gender,age,dialysis age,smoking history,drinking history,primary disease;2.(1)Comparison of biochemical indicators: ALb(36.40 ± 4.10),Hb(102.00 ± 4.77),Ca(2.15 ±0.21))Were higher than those with insufficient dialysis(33.66 ± 3.82),(91.33 ± 3.55),(1.86 ±0.2);P(2.04 ± 0.1)and i PTH(244.07 ± 25.03)were lower than those with insufficient dialysis P(2.18 ± 0.1)and i PTH(293.29 ± 25.02)were statistically significant(P<0.05).(2)The total physical health score(PCS)(59.18 ± 5.22),total mental health score(MCS)(58.68 ± 4.01),and comprehensive score(58.93 ± 3.53)of the SF-36 scale in the adequate dialysis group were higher than inadequate dialysis.There were significant differences in the(54.35 ± 5.39),(53.53± 4.18),and(53.94 ± 3.08)groups(P<0.05).3.Spearman correlation analysis was used to show the dialysis adequacy(Kt/V value)and the total physical health score(PCS)(r = 0.400,P <0.01)and the total mental health score(MCS)(r= 0.553,P<0.01)and the overall score(r = 0.680,P<0.01)were positively correlated in the SF-36 scale.It was positively correlated with ALb(r =0.270,P<0.01),Hb(r = 0.606,P<0.01),and Ca(r = 0.564,P <0.01).It was negatively correlated with P(r =-0.460,P<0.01)and i PTH(r =-0.667,P<0.01).Conclusions: 1.There is a correlation between dialysis adequacy(Kt/V value)and quality of life in patients with MHD.2.Adequate hemodialysis can improve hemoglobin,albumin,blood calcium,blood phosphorus,and full-parathyroid hormone levels,improve malnutrition,correct calcium and phosphorus metabolism disorders,reduce complications,and improve the quality of life of patients with MHD.3.Adequate hemodialysis can improve the physical and mental health of patients with MHD.Improving the adequacy of dialysis as soon as possible is beneficial to improving the quality of life of patients with MHD.