| Objective: To investigate the influencing factors related to early postoperative lower urinary tract symptoms in patients with benign prostatic hyperplasia(BPH),and to provide relevant reference for clinical prevention of early postoperative lower urinary tract symptoms in BPH.Methods: Retrospective analysis of 233 patients who underwent prostate enlargement surgery in Suining Central Hospital and Shehong People’s Hospital from January 2019 to October 2020 was conducted.Among them,166 patients underwent transurethral resection of prostate(TURP)in Suining Central Hospital and 67 patients underwent holmium laser enucleation of prostate(Ho LEP)in Shehong People’s Hospital.The clinical data of the study subjects were collected,including age,body mass index(BMI),preoperative prostate volume(V),surgical method,preoperative and postoperative International Prostate Symptom Score(IPSS score),preoperative urinary flow rate examination(maximum urinary flow rate,residual urine,etc.),and the occurrence of postoperative LUTS were recorded.Among 233 patients,they were divided into LUTS group and non-LUTS group according to whether lower urinary tract symptoms(LUTS)were still present at one month after surgery,and they were divided into prostate electrosurgery group(TURP group)and holmium laser enucleation group(Ho LEP group)according to the surgical method.Then the data were analyzed statistically,single factors analysis using independent sample t test,chi square test,single factors analysis showed that the factors with P < 0.05 were analyzed using multivariate binary logistic regression model to understand the relationship between related indicators and early postoperative LUTS.Results: Among the 233 patients,there were 166 patients in TURP group,and 13 patients had LUTS one month after operation,among which,there were 10 patients with urinary storage symptoms and 3 patients with urinary voiding symptoms.While there were67 patients in the Ho LEP group,and 7 patients had LUTS one month after operation,among which,there were 4 patients with storage symptoms,2 patients with urinary voiding symptoms and 1 patient with post urination symptoms.By chi square test,the p value was0.519,P > 0.05,the difference was not statistically significant.Compared with non LUTS group,the average age of LUTS group was 69.85 ± 5.98,and the mean age of patients in non LUTS group was 69.78 ± 6.71,P value was 0.305,P > 0.05,the difference was not statistically significant.The mean BMI of LUTS group was 25.00 ± 2.19,and the mean BMI of non LUTS group was 24.72 ± 2.18,P value was 0.593,P > 0.05,the difference was not statistically significant.The mean preoperative IPSS score of LUTS group was15.50 ± 1.73,and the mean IPSS score of non LUTS group was 11.35 ± 2.74,P < 0.001,the difference was statistically significant.The mean preoperative prostate volume of LUTS group was 80.56 ± 28.63,and the mean preoperative prostate volume of non LUTS group was 46.80 ± 21.25,P < 0.001,the difference was statistically significant.The mean preoperative residual urine of LUTS group was 193.60 ± 102.59,and the mean value of preoperative residual urine in non LUTS group was 42.93 ± 73.73,P < 0.001,the difference was statistically significant.The mean preoperative maximum flow rate of LUTS group was 4.20 ± 1.23,and the mean preoperative maximum flow rate in the non LUTS group was 8.18 ± 2.59,P < 0.001,the difference was statistically significant.Multivariate logistic regression analysis showed that preoperative IPSS score(OR = 1.556,95% CI = 1.057-2.29,P = 0.025)and preoperative prostate volume(OR = 1.015,95% CI =0.996-1.035,P = 0.001)were the main factors for postoperative LUTS.Conclusion: 1.Preoperative IPSS score,preoperative prostate volume,preoperative residual urine and preoperative maximum urinary flow rate were the factors leading to postoperative LUTS.2.LUTS after operation mainly manifested as the urinary storage symptoms.3.There was no effect of operation methods on LUTS. |
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