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Clinical Study Of Jianbuhuqianwan Decoction Combined With PVP In The Treatment Of Osteoporosis Thoracolumbar Fracture Due To Liver And Kidney Deficiency

Posted on:2022-07-01Degree:MasterType:Thesis
Country:ChinaCandidate:J Q WengFull Text:PDF
GTID:2504306521999039Subject:Orthopedics scientific
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Objective: To explore the clinical efficacy of Jianbuhuqianwan decoction combined with percutaneous vertebro plasty in the treatment of osteoporotic thoracolumbar fractures due to liver and kidney deficiency,in order to find an effective treatment which combination with Chinese and Western medicine to treat the osteoporotic thoracolumbar fractures.Methods: Patients with osteoporotic thoracolumbar fractures who were hospitalized in the second Department of Orthopedics and Traumatology of the Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine from January 2019 to June 2020 were selected.In this experiment,a total of 60 patients with osteoporotic thoracolumbar fractures were collected.According to the random number table,they were divided into observation group and control group with 30 cases each.During the experiment,3 cases occurred and 2 case was eliminated.Among them,1case in the observation group failed to follow up regularly,and 1 case had gastrointestinal discomfort due to oral administration of Chinese medicine;2 cases in the control group failed to follow up regularly,and1 case took orally related analgesics during the treatment.Finally,28 cases in the observation group and 27 cases in the control group were collected.A total of 55 cases were actually collected.The patients in the control group were given percutaneous vertebro plasty and conventional anti-osteoporosis drugs after the operation(Calci D amd Alfacalcidol).The observation group was treated with jianbuhuqianwan decoction on the basis of the treatment of the control group.The NRS pain score,ODI score,and vertebral height loss rate were recorded and compared before operation,1 day after operation,1 month after operation,and 3 months after operation.The bone mineral density were recorded and compared before operation and 6 months after operation.result:Two groups of patients were compared in gender,age,and injured vertebral disease(P >0.05),which was comparable.The NRS pain of two groups were compared preoperative[(8.21±1.24)vs(8.15±1.18),(3.96±1.05)vs(3.89±1.31)](P >0.05),indicating the differences of pain between the two groups of cases preoperatively were comparableand and in terms of pain relief after the operation are negligible.In 1 month and 3 month,NRS pain scores between the two groups were compared [(2.61 ± 0.57),(1.96 ± 0.50),(2.37 ± 0.55)],(P<0.05),description Combined with the Jianbuhuqianwan decoction group has a better effect in improving the pain of patients.The ODI score of two groups were compared preoperative(%)(63.04± 8.72)vs(63.04 ± 8.72)vs(37.78 ± 7.21)](37.78 ± 7.21)](37.78± 7.21)](P >0.05),indicating the differences of The ODI score between the two groups of cases preoperatively were comparableand and in terms of impacting on functional mobility are negligible.In 1 month and 3month,ODI scores between the two groups were compared [(27.78 ± 6.44)vs(32.21 ± 5.21)VS(23.21 ± 5.90)],(P<0.05),explanation It has a better effect in improving patient functionality activities using Jianbuhuqianwan decoction.The vertebral height loss rate of two groups were compared preoperative(%)(43.02 ± 9.09)vs(42.02 ± 10.00),(30.89 ± 8.02)vs(30.64 ± 9.02)](P >0.05),indicating the differences of vertebral height loss rate between the two groups of cases preoperatively were comparable and and in terms of impacting on vertebral height are negligible.Comparison of vertebral height loss rate(%)between the two groups at 1 month after operation(31.20±8.83)vs(32.43±9.18)(P>0.05),comparison of vertebral height loss rate(%)between the two groups at 3 months after operation(31.23±9.33)vs(36.12±8.09)(P <0.05),indicating that the combined use of Jianbuhuqianwan decoction group has a better effect in preventing the loss of vertebral height.The bone mineral density of two groups were compared preoperative(-3.21 ± 0.44)vs(-3.30 ± 0.44)(P >0.05),which was comparable;6month after surgery,compared between the bone density value between the two groups(-2.82 ± 0.38)VS(-3.06 ± 0.37)(P <0.05),explaining that the joint use of Jianbuhuqianwan decoction group has a better effect in improving bone mineral density.The clinical efficiency of each group was compared after treatment.The total efficiency of observation group was 96.4%,while the total efficiency of the control group was 85.2%.(P <0.05).This indicates that the clinical efficacy of the combined with Jianbuhuqianwan decoction was better.Conclusion: For the treatment of patients with osteoporotic fractures due to liver and kidney deficiency,the combination of Jianbuhuqianwan decoction with conventional anti-osteoporosis treatment after percutaneous vertebro plasty can better reduce the patient’s pain,improve the patient’s movement function,prevent further loss of vertebral height and enhance bone mineral density.
Keywords/Search Tags:Osteoporosis thoracolumbar fracture, Jianbuhuqianwan decoction, Percutaneous vertebro plasty, clinical study
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