Clinical Study On Between TCM Syndromes Of Non-valvular Atrial Fibrillation And CHA2DS2-VASc,Atrial Fibrillation Burden And Other Objective Indicators

Research purposes :This topic through statistical analysis of non-valvular atrial fibrillation TCM syndrome differentiation and general condition data,CHA2DS2-VASc score,atrial fibrillation burden,thrombosis related objective indicators,echocardiography and other related indicators of correlation,make TCM syndrome differentiation more objective,for the safe treatment of traditional Chinese medicine atrial fibrillation,predict the risk of thrombosis,provide reference basis.Research methods :The population was chosen to the study who were admitted to the Cardiovascular Department of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine who met the inclusion criteria for non-valvular atrial fibrillation,from February 2019,to January 2020who the non-valve atrium tremor integrates the standard to take the object of study.The Chinese medicine four examines the information(TCM)of the research objects were collected and classified according to the syndrome differentiation in this study.The general case data such as gender,age,height,weight,history of tobacco and alcohol,and past medical history were collected.The average platelet volume,BNP,coagulation function,The cardiac cardiovascular colour Doppler and other correlations were used.A new database was created and SPSS 23.0was applied for data handling and the statistical evaluation.Results :1 The TCM syndrome distribution of non-valvular atrial fibrillation was as follows: the lacking in vital energy blood stasis card > the painstaking care stasis anti-card > the asthma harasses the heart card > qi and yin deficiency syndrome > guilty conscience and timidity syndrome >drinking water and spirit heart syndrome.2 The sex ratio of nonvalvular atrial fibrillation patients was female > male,p < 0.01,with statistical difference.The relationship between different TCM syndrome types and gender,p >0.05,was not statistically different.3 The mean age of the patients with non-valvular atrial fibrillation was significantly higher in the Heart Deficiency and Timidity Certificate group than in the Water Drinking and Heart Stasis Certificate group and the Phlegm and Qi deficiency and blood stasis evidence group and Fire Disturbing the Heart group,all p < 0.01.The mean age in the Heart Deficiency and Timidity Certificate group was significantly lower than in the Qi-Yin Two Deficiency Certificate group,the Water Drinking and Heart Stasis Certificate group,the Qi Deficiency and Blood Stasis Certificate group,and the Phlegm and Fire Disturbing the Heart Certificate group and the Heart Blood Stasis Certificate group,all p < 0.01.The mean age was significantly lower in the group with p < 0.01.4.Drinks the juicy heart synthesis to draft the treatment the non-valve room to tremble the patient to drink wine the history to account for the proportion to be higher than the painstaking care stasis anti-card and the lacking in vital energy blood stasis card patient obviously(p <0.05).5.The percentages of non-valvular atrial fibrillation patients with a low BMI and a normal BMI were significantly higher than those with phlegm-heat internal disturbance,heart-blood stasis and water-drink overflowing the heart,all p < 0.01.The potable water excessive synthesis drafts the BMI overload,the BMI obese proportion is higher than the lacking in vital energy blood stasis card,the gas obviously cloudy two empty proves(P < 0.01).6.The most frequently observed concomitant diseases in patients with non-valvular atrial fibrillation were high blood pressure(73.4%),followed by heart failure(52.0%),coronary heart disease(46.7%),and stroke(43.2%)and type 2 diabetes mellitus(31.3%).The proportion of patients with non-valvular atrial fibrillation with heart failure associated with water-drinking evidence was highest,significantly higher than that of patients with phlegm-heat internal syndrome disturbance evidence and heart deficiency and timid syndrome,qi deficiency and blood stasis syndrome,p < 0.01.The proportion of central blood stasis syndrome combined with coronary heart disease in patients with non-valvular atrial fibrillation was the highest,which was significantly higher than that of heart deficiency and timidity syndrome and qi deficiency and blood stasis syndrome,p < 0.01.7.The non-valve sickness atrium tremor partner potable water excessive heart synthesis drafts patient’s MVP to be higher than the lacking in vital energy blood stasis,the phlegm hot detuning,the timid patient,p < 0.05.The blood stasis card group FIB level is higher than the timid card group,Lacking in vital energy blood stasis card group friendly cloudy two empty card group comparison,p < 0.05.The painstaking care stasis anti-card group D-dimer level is higher than the timid card group,the lacking in vital energy blood stasis card group and the phlegm hot detuning card group obviously,p < 0.01.The concentration of the D-dimers was much greater in the water-drinking syndrome group than in the heart-deficiency and timidity syndrome group,the qi-deficiency and blood-stasis syndrome group and the phlegm-heat internal disturbance syndrome group,p < 0.05.8.In patients with non-valvular atrial fibrillation,water-yin-ling-heart card group BNP level is higher than the timid card group,the lacking in vital energy blood stasis card group,the phlegm obviously harasses the card group,the painstaking care stasis anti-card group hotly,p< 0.01.water-yin-ling-heart group BNP level is higher than is mad the cloudy two empty card group,P < 0.05.Is unexpectedly cloudy two spatial group’s BNP levels is higher than the shy group,the blood circulation group’s gaps and omissions condition and phlegm causes this group of badly battered obviously,p < 0.01.9.CHOL levels in patients with non-valvular atrial fibrillation in the phlegm-heat disturbance group were higher than those in the water-yin-ling heart syndrome group and qi-yin deficiency syndrome group,p < 0.05.The lacking in vital energy blood stasis card group,the phlegm harasses card group TG to be higher than obviously hotly is mad the cloudy two empty card group and the hot brewed tea card group,p < 0.01.10.The non-valve hospital ward trembles the painstaking care stasis anti-card patient CHA2DS2-VASc grading to be higher than the timid card group,Gas false blood evidence group,asthma obvious harassment heart evidence group,p < 0.01 timid evidence group CHA2DS2-VASc score is significantly lower than the gas false blood evidence group,phlegm fire disturbing heart syndrome group,water drinking Lingxin syndrome group,qi and yin deficiency syndrome group,heart blood stasis group,p < 0.01.11.The HAS-BLED marks in those with non-valvular atrial fibrillation were significantly more in the Heart and Blood Stasis Certificate group than in the Heart Deficiency and Choleric Certificate group and the Qi Deficiency and Blood Stasis Certificate group,all at p < 0.05.The HAS-BLED scores of the Heart Deficiency and Timidity Certificate group were significantly lower than those of the Qi Deficiency and Blood Stasis Certificate group,the Phlegm and Fire Disturbing the Heart Certificate group and the phlegm fire disturbing heart syndrome group,water drinking Lingxin syndrome group,qi and yin deficiency syndrome group,heart blood stasis group,p < 0.01.12.The non-valve atrium tremor patient painstaking care stasis anti-card apoplexy risk rank obviously is higher than the timid card group,the lacking in vital energy blood stasis card group,p < 0.01,the painstaking care stasis anti-card apoplexy risk rank is higher than the asthma to harass the heart card group,p < 0.05.Panic-stricken group stroke risk grading is lower than the vitality real diagnosis group,the asthma obviously harasses the heart card group,water drinking Lingxin syndrome group,qi and yin deficiency syndrome group,heart blood stasis group,p <0.01.13.The proportion of stroke history in nonvalvular atrial fibrillation high burden group was higher than that in atrial fibrillation low burden group,p < 0.05.The risk of stroke in the high burden group was higher than that in the low burden group.The linear relationship between the burden of atrial fibrillation and the risk of stroke in nonvalvular disease was weak,and the correlation coefficient was less than 0.5.14.There were substancially statistically significant variations in left atrial size,right atrial size,left ventricular end-diastolic internal diameter,right ventricular size,lung artery pressure and left ventricular ejection fraction in patients with non-valvular atrial fibrillation in the different TCM evidence groups,all p < 0.01.The left atrial size,the non-valve atrial fibrillation patients in the water yin-ling heart syndrome group had the right atrial size,the left ventricle diastole last stage diameter and the pulmonary artery press obviously are higher than the vacation gas blood clot group.Timid card group,phlegm hot card group,blood stasis card group,p < 0.01;water-yin Lingxin the group left room shoots the menstruation number to be lower than obviously is mad the cloudy two empty card group,the phlegm hot card group,the blood stasis card group,the lacking in vital energy blood stasis card group and the timid card group,p <0.01.Left atrial size,right atrial size in patients with nonvalvular atrial fibrillation in Qi-yin deficiency syndrome group were higher than those in Qi deficiency and blood stasis syndrome group and heart deficiency and timidity syndrome group,Group with internal disturbance of phlegm and heat,and group with stagnation of heart and blood(p<0.05);The size of left heart ventricular ejection fraction was substantially lower in the group with Water Drinking overtaking the heart than in the group with Phlegm-Heat internal disturbance,Qi deficiency and Blood stasis,and Heart deficiency and Cowardice,all at p< 0.01.The left ventricular enddiastolic internal diameter of patients with non-valvular atrial fibrillation in the Qi-Yin Two deficiency group was higher than that in the Cardiac Blood Stasis group,with p < 0.05,a difference of statistical value;the pulmonary artery pressure of patients with non-valvular atrial fibrillation in the Qi-Yin Two deficiency group was remarkably higher than that in the Heart Deficiency and Cholerism group and the Qi Deficiency and Blood Stasis group,with p < 0.01,a significant difference of statistical value;the left ventricular ejection fraction size in the QiYin Two deficiency group was significantly lower than that in the Heart Deficiency and Cholerism group,the Phlegm-Heat Internal Disturbance group,the Qi Deficiency and Blood Stasis group,with p < 0.01,a statistically significant difference of Statistic value.The left ventricular ejection fraction size in the Qi-Yin deficiency group was considerably lower than that in the Heart deficiency and timidity group,the Phlegm-Heat internal disturbance group,the Qi and Blood stasis group and the Heart deficiency and timidity group,all with p < 0.01,which was statistically insignificant.Research conclusions :1The distribution of TCM syndromes of nonvalvular atrial fibrillation is :The lacking in vital energy blood stasis card > the painstaking care stasis anti-card > the asthma harasses the heart card > to be mad the cloudy two empty cards > the timid card > drinks the juicy heart card.2 Non-valvular atrial fibrillation patients with blood stasis syndrome group of non-valvular atrial fibrillation patients with the highest average age,combined with hypertension,cardiac failure,cardiovascular disease,Stroke and type 2 of diabetes mellitus high percentages.The highest CHA2DS2-VASc score and the highest risk of stroke level in evidence of cardiac blood stasis in patients with non-valvular atrial fibrillation,the painstaking care stasis anti-card thrombus index of correlation is highest.The non-valve room trembles patient’s main center blood stasis card friendly cloudy two empty card HAS-BLED grading to be high.3.The timid card group average age is lowest,hypertension,the heart failure,coronary disease,the apoplexy,2 diabetes proportions are low.At the same time,CHA2DS2-the VASc grading,apoplexy risk grading and the HAS-BLED grading are lowest.4.Non-valve Fang Changao shoulders the group the apoplexy history proportion to be higher than Fang Chandi to shoulder the group obviously.5.Non-valve room tremble in the patient,Shui Yinling the heart card group friendly cloudy two empty card group heart failure proportion is high,BNP,the heart increase with the heart function drop obviously.