Analysis Of Risk Factors Of Early Portal Vein Complications Stage After Pediatric Living Donor Liver Transplantation

Purpose To explore the risk factors of early portal vein complications after pediatric living donor liver transplantation,and to reduce the incidence of early portal complications after surgery.Methods Retrospective case-control analysis was used.From June2018 to December 2019,the clinical data of 50 cases of pediatric living donor liver transplantation in Children’s Hospital of Chongqing Medical University were collected.Univariate and multivariate analysis were applied to identify the risk factors of early portal vein complications after pediatric living donor liver transplantation.Results Among the 50 children undergoing living donor liver transplantation,30 were males and 20 were females.9 cases of portal vein complications occurred after surgery,including 4 cases of portal vein flow anomalies,3 cases of portal vein thrombosis,and 2 cases of portal vein stenosis.46 cases of the primary disease were biliary atresia.Univariate analysis showed that there was a statistical difference between the portal vein complications group and the control group in gender and whether GRWR was ≥4%(P<0.05).Multivariate logistic regression analysis showed that the diameter of the recipient portal vein was less than 5mm(P=0.037,OR=12.39,95% confidence interval 1.16 to 132.38),and GRWR≥4%(P=0.031,OR=8.023,,95% confidence interval 1.21 to 53.18)were independent risk factors for early portal vein complications.Conclusions Too small recipient portal vein and excessive GRWR are independent risk factors for postoperative complications of portal vein.The diameter of recipient portal vein should be carefully evaluated and the size of GRWR should be controlled before surgery,which can reduce the incidence of early portal vein complications.