Data Analysis And Preliminary Exploration Of Chongqing Eye Bank In 20 Years

Purpose:This study aimed to analyze corneal transplantation trends and voluntary donor characteristics at the Chongqing Eye Bank in China.Methods:We retrospectively reviewed and analyzed data from January 1,1999,to December 31,2018,covering 5,397 preregistered voluntary donors,1955 actual donors 3,910 donated tissues and 2,374corneal transplantations.Results:The 5,397 preregistered donors included 13 ethnic groups,an overall mean age of 39.6 years.Of the 1955 actual donors,the male-to-female ratio was 3.3,and the mean age was 57.1±23.0 years.Based on population size in 2018,the Jiangbei county was the most active in donation willingness,with 60×10^-6per capita,and the Yuzhong county was the most active in cornea donations,with 45×10^-6per capita.Of the3,910 donated corneas,2,540（65.0%）were clinically used.Of those not used,978（71.4%）were rejected for poor corneal quality.The 2,374 corneal transplantation procedures included 1,671 penetrating keratoplasty（70.39%）,700 lamellar keratoplasty（29.49%）,and three corneal endothelial transplantations in our center（0.13%）.Infectious keratitis（37.0%）was the leading indication for keratoplasty.Conclusion:Our study reports corneal donation and transplantation trends in Chongqing over 20 years,showing that infectious keratitis is a leading indication for keratoplasty.The analysis further suggests that a potential preregistered cornea donor is a female,with a higher education level.