Numerical Simulation Analysis Of Personalized Saccular Aneurysm Rupture

Cerebral aneurysm is a cerebrovascular disease characterized by local swelling of blood vessels.Once the aneurysm ruptures,it is extremely harmful.However,the occurrence,development and rupture mechanism of aneurysms are still unclear.Related studies have pointed out that hemodynamics plays an important role in the formation and rupture of aneurysms.Therefore,the use of hydrodynamic methods is of great significance to the study of hemodynamic parameters of aneurysms.Previously,scholars have performed numerical calculation and analysis on aneurysms,but most people use two-dimensional or three-dimensional idealized models for analysis and research,which cannot accurately express the true biomechanical conditions of cerebral aneurysms.Therefore,the use of medical data images to reconstruct an aneurysm model to simulate the real blood flow environment and study the dynamic parameters of cerebral aneurysm is of great significance to explain the occurrence and development of aneurysm.The cervical aneurysm model established in this paper is completed by selecting CT tomographic images of patients with cerebral aneurysm.The true height of the model restores the true geometry of the aneurysm,and the fluid-structure coupling calculation method is used to calculate the fluid domain and solid domain of the aneurysm.Calculation.According to the analysis theory of fluid-structure coupling,the two-way coupling analysis of aneurysm is completed.The fluid domain considers the aneurysm velocity,wall shear and wall pressure;the solid domain mainly analyzes the deformation of the aneurysm.Through analysis,it is found that the deformation of the aneurysm is mainly at the top of the aneurysm and the neck of the aneurysm.The wall shear force and blood flow rate at the top of the aneurysm are slow,and the blood on the side of the aneurysm has long-term impact,so the risk of rupture at the top of the aneurysm It is higher,and the aneurysm on the side of the aneurysm is more likely to continue to grow;using statistical methods to study the factors of aneurysm rupture,the best predictive value of rupture is obtained.The comparison shows that the size parameters of the threedimensional reconstruction model are much higher than the predicted value of rupture,and the aneurysm ruptures The risk is greater.Through analysis and research on Newtonian and non-Newtonian fluid characteristic models.The results show that the two blood models have a large gap,especially the difference in the numerical value of the wall shear force;but the Newtonian model and the non-Newtonian model have the same change law.By comparing the boundary conditions of different intracranial pressure,it is found that the aneurysm under high intracranial pressure is characterized by low wall deformation,high blood velocity and high wall shear force;low intracranial pressure conditions are represented by high wall deformation,low blood flow rate,and low wall surface.Shear force.Therefore,high intracranial pressure of aneurysm makes the aneurysm more likely to grow,and low intracranial pressure leads to a greater risk of aneurysm rupture.In this paper,a three-dimensional aneurysm model is established through medical imaging,fluid-structure coupling methods and statistics are used to analyze and explore the risk of aneurysm rupture.At the same time,different fluid regimes and intracranial pressure boundary aneurysm hemodynamic changes are compared.It provides a certain reference value for personalized analysis of aneurysm rupture.