Individual Influencing Factors Of The Electrophysiological Severity In Carpal Tunnel Syndrome

Background and Aim: Carpal tunnel syndrome(CTS)is the most common single peripheral neuropathy.The main syndromes of CTS include numbness,pain,loss of strength and muscle atrophy of the radial 3? digits.The disease affects people’s daily lives and work.Electromyography examination(EDX)is not only the golden standard of diagnosing CTS,but also a guide in treating and predicting the prognosis of the CTS.It has been cleared about risk factors in the onset of CTS,but influencing factors of the electrophysiological severity in CTS have not yet been clarified.In China,there has been no such study yet,therefore the aim of this study is to evaluate relationship between gender,age,duration of the disease,body mass index(BMI),anthropometric measurements(i.e.,wrist circumstance,wrist width)and the electrophysiological severity of CTS.Method: This is a retrospective,descriptive study.Study sample consist of 161 patients diagnosed with CTS.The demography(i.e.,gender,age,height,weight and BMI),EDX result and body measurements included wrist circumstance,wrist width of all the patients were collected and analyzed.Bland scale was used to grading the electrophysiological severity of the CTS patients.Statistical analyses were performed using the software SPSS25.0.Demographic data were analyzed by analysis of variance and Chi-square tests were used to evaluate group differences among different severities and factors like gender,age etc.Multiply regression analysis and Spearman correlation analysis were used to evaluate the relationship between influencing factors and the electrophysiological severity of CTS.A p value of less than 0.05 was taken to be statistically significant.Result: Patients in this study have an average age of 49.07±10.23 years old.There were more women in this study(female 131: male 30).The study indicates that gender,BMI and wrist circumstance have no impact on CTS electrophysiological severity.In female subgroup,wrist width and duration of CTS were different among the three severities.Therefore wrist circumstance/wrist width was different among the three severities in male subgroup.Ordinal multiply regression analysis suggests that the duration of the disease(OR:1.011,95%CI:1.002-1.019)and wrist width(OR:1.211,95%CI:1.068-1.374)were both independent risk factors of electrophysiological severity in females.While there is no clear relationship between wrist circumstance/wrist width and the electrophysiological severity in males.Conclusion: The duration of CTS and wrist width were both independent risk factors of electrophysiological severity in female CTS patients.Furthermore,the longer the duration of the disease,the more severe CTS patients might have.And wider wrist widths might imply the more severe CTS cases.