Clinical Effect Analysis Of Arthroscopic Microfracture Combined With Autologous Collagen-induced Chondrogenesis In The Treatment Of Knee Cartilage Defect

Objective: To investigate the clinical effect of arthroscopic microfracture combined with autologous collagen-induced chondrogenesis in the treatment of knee cartilage defect.Method: Using a random number table method to divide 24 patients with knee cartilage injury who were treated in the Department of sports medicine of the Third Hospital of Hebei Medical University from March 2019 to March2020 into two groups,12 cases in the ACIC group were treated with arthroscopic microfracture combined with autologous collagen-induced chondrogenesis;12 cases in the MF group were treated with arthroscopic microfracture.We compared the MOCART、IKDC、Lysholm、VAS scores and total effective rate of the two groups.Results:The MOCART scores of the ACIC group increased from5.0(0.0～8.8)before operation to(72.1±7.5)after operation(P<0.05),and the score of the MF group increased from 5.0(0.0～8.8)to(45.8±8.2)(P<0.05).The scores of the two groups were compared 12 months after operation(P<0.05),and the difference was statistically significant;The IKDC scores of the ACIC group increased from(60.0±8.1)before operation to(74.1±8.5)after operation(P<0.05),and the score of the MF group increased from(56.5±10.2)to(75.8±6.6)(P<0.05).The scores of the two groups were compared 12 months after operation(P>0.05),and the difference was not statistically significant;The Lysholm scores of the ACIC group increased from(65.7±13.6)before operation to(83.3±7.1)after operation(P<0.05),and the scores of the MF group increased from(62.1±14.7)to(82.9±8.5)(P<0.05).The scores of the two groups were compared 12 months after operation(P>0.05),and the difference was not statistically significant;The VAS scores of the two groups were compared 12 months after operation,and there was no significant difference between the ACIC group(1.3±0.9)and the MF group(1.6±1.0)(P>0.05).The effective rates of the ACIC group and the MF group were 91.67% and 83.33% respectively,and the difference was not statistically significant(P>0.05).Conclusion: Both ACIC and microfracture can achieve satisfactory short-term results in the treatment of articular cartilage defects,but the MOCART score of the ACIC group was significantly higher than that of MF group.MRI observation of cartilage repair evaluation standard shows that the ACIC can improve the filling rate of cartilage defect repair,promote the fusion of the filler and adjacent normal cartilage,and the internal structure stratification,tissue morphology,signal intensity of repair tissue are closer to normal hyaline cartilage,which can effectively improve the prognosis and promote the cartilage repair of patients.