Analysis Of Etiological Types,Risk Factors And Prognosis Of Cerebral Infarction In Young Adults Aged 18-34 Years

Objective: To investigate the classification,risk factors and prognosis of cerebral infarction in young adults aged 18 to 34 years.By improving people’s understanding of the disease,this part of young stroke patients can do well in the early prevention,early detection,early treatment of young cerebral infarction,which lower the incidence,disability and mortality rate.Methods:1.This study retrospectively analyzed the case data of 112 young cerebral infarction patients aged 18-34 years who were hospitalized in the Department of Neurology of our hospital from February 2018 to October 2019,and analyzed the risk factors of different etiology types of young cerebral infarction patients aged 18-34 years.2.According to the MRS score,the patients were divided into the good prognosis group and the poor prognosis group.The influence of risk factors on the prognosis of young cerebral infarction patients aged 18-34 years was analyzed by binary Logistic regression analysis.Results: 1.A total of 112 subjects were included in this study,including91 males(81.2%)and 21 females(18.8%).According to Toast classification,there were 58 cases(51.70%)of large artery atherosclerosis type,12 cases(10.7%)of cerebral embolism type,0 cases of small artery occlusion type,17cases(15.2%)of stoke of other determined cause,and 25 cases(22.3%)of stoke of undetermined cause.Most of the symptoms of young cerebral infarction aged 18-34 years were mild(NIHSS≤4 72.3%),with good prognosis and no symptoms at all(MRS<1 61.7%).2.the results of single factor χ2 test analysing The cause of different types of risk factors show that gender,smoking,drinking,hypertension,hyperlipidemia,cholesterol,low-density lipoprotein,hyperhomocysteinemia(P<0.05)in the large artery atherosclerosis type of young cerebral infarction patients aged 18-34 years are statistically significant;hypertension,hyperlipidemia,triglyceride,history of stroke(P<0.05)in the cerebral embolism type of young cerebral infarction patients aged 18-34 years are statistically significant;gender,smoking and drinking(P<0.05)had statistical significance in the stoke of other determined cause type of young patients aged 18-34 years with cerebral infarction.Binary Logistic regression analysis showed that smoking(OR=3.891,P=0.002),hypertension(OR=2.379,P=0.047),low-density lipoprotein(OR=4.487,P=0.007),and hyperhomocysteinemia(OR=2.537,P=0.048)are associated with risk factors of large artery atherosclerosis type in young patients aged18-34 years with cerebral infarction.Previous stroke history(OR=7.163,P=0.049)was a risk factor for cerebral embolism in young patients aged 18-34 years with cerebral infarction.Gender(OR=6.675,P=0.002)was the risk factor of stoke of other determined cause type in young patients aged 18-34 years with cerebral infarction.3.Univariate analysis of poor prognosis shows that the proportion of male patients in the poor prognosis group was higher than that in the good prognosis group(P=0.035).Binary Logistic regression analysis showed that gender(OR=3.332,P=0.014)and hypertension(OR=4.047,P=0.044)are independent risk factors for poor prognosis of young patients aged 18-34 years with cerebral infarction.Conclusions:1.Smoking,hypertension,elevated low density lipoprotein,and hyperhomocysteinemia are risk factors for the large artery atherosclerosis type in young patients aged 18-34 years with cerebral infarction.2.Patients with previous stroke history were risk factors for the cerebral embolism type in young patients aged 18-34 years with cerebral infarction.3.Male and hypertension are independent risk factors for poor prognosis of young patients aged 18-34 years with cerebral infarction.