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Type 2 Diabetes Mellitus With Coronary Heart Disease Research On The Distribution Of TCM Syndrome Types

Posted on:2022-09-17Degree:MasterType:Thesis
Country:ChinaCandidate:X Y ChenFull Text:PDF
GTID:2504306557472874Subject:Chinese medical science
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Objective : To analyze the epidemiological characteristics of type 2diabetes complicated with coronary heart disease(Xiaoke disease and chest obstruction)and the distribution of TCM syndrome types,and explore the correlation between various syndrome types and clinical indicators,in order to provide science for the prevention,syndrome differentiation and treatment of the disease The basis for better guidance of clinical work.Method:This subject uses retrospective research as the basic investigation method,and collects 500 case data of inpatients with type 2 diabetes and coronary heart disease in the Department of Endocrinology,Yinchuan Traditional Chinese Medicine Hospital from January 2014 to November 2020 according to the diagnosis,inclusion and exclusion criteria.,Three physicians with TCM physician qualification certificates in the Department of Endocrinology will perform TCM syndrome differentiation(including the attending physician,deputy chief physician or chief physician)for qualified cases.Fill in the case information collection form in accordance with the regulations(including the patient’s general condition,past history,laboratory data,and four-diagnosis data of traditional Chinese medicine).Establish a database,use SPSS26.0 software for statistical analysis,mainly use frequency analysis,logistic regression analysis,etc.to analyze the epidemiology of type 2 diabetes with coronary heart disease,the distribution of TCM syndromes,and the relationship between TCM syndromes and clinical indicators Correlation.Result:1.Among the 500 T2 DM patients with CHD,76.6% were over 60 years old;67% were patients with BMI ≥ 24;383 cases(76.6%)with hypertension from high to low frequency of complications> 347 cases with peripheral neuropathy(69.8%)> 312 cases with arteriosclerosis(62.4)> 188 cases(37.6%)with fatty liver> 114(22.8%)diabetic nephropathy> 108 cases(21.6%)with hyperlipidemia> 47(9.5%)with diabetic foot> Diabetic retinopathy 41(8.2%)>diabetic gastroparesis 19(3.8%).2.500 cases of T2 DM combined with CHD TCM syndrome distribution:(1)Main syndrome: Qi and Yin deficiency(51.6%)> Liver and kidney Yin deficiency(30.2%)> Yin and Yang deficiency(18.2%);(2)Concurrent Symptoms:blood stasis syndrome> phlegm turbidity and blood stasis syndrome> qi stagnation and blood stasis syndrome> phlegm turbidity syndrome> qi stagnation syndrome;(3)compound syndrome type: deficiency of both qi and yin and blood stasis syndrome,liver and kidney yin deficiency and blood stasis syndrome,Yin and Yang deficiency and blood stasis syndrome,qi and yin deficiency syndrome,liver and kidney yin deficiency syndrome,qi and yin deficiency and phlegm stasis syndrome,qi and yin deficiency and qi stagnation syndrome,yin and yang deficiency syndrome.3.Taking Yin and Yang deficiency syndrome as a reference indicator,the results of multi-class logistic regression analysis of specific syndrome types:(1)Significant indicators of independent variables included in Qi and Yin deficiency syndrome include age,diabetes course,BMI,GLU.Patients who were 45-59 years old(P=0.013,OR=3.189)were more likely to develop Qi and Yin deficiency syndrome than those who were 75-89 years old,and the risk of occurrence was3.189 times.Patients with diabetes duration equal to 5-15 years(P=0.023,OR=2.232)are more prone to develop Qi and Yin deficiency syndrome than those with diabetes duration> 15,and the risk of occurrence is 2.232 times.Patients with BMI>28(P=0.034,OR=0.234)are more likely to have Qi and Yin deficiency syndrome than those with BMI less than 18.5,and the risk of occurrence is 0.234 times.Patients with decreased GLU(P=0.00)were more likely to have deficiency of both qi and yin than patients with increased GLU.(2)Significant indicators of the independent variables included in the syndrome of liver and kidney yin deficiency include BMI and diabetic retinopathy.Patients with a BMI greater than28 are more likely to have liver and kidney yin deficiency than those with a BMI less than 18.5(P=0.049,OR=0.105),and the risk of occurrence is 0.15 times.Patients with diabetic retinopathy(P=0.042,OR=3.556)are 3.556 times more likely to have liver and kidney yin deficiency than those without diabetic retinopathy.Conclusion:1.Through research and analysis,it is further confirmed that patients with T2 DM combined with CHD are mainly middle-aged and elderly people,and overweight and obesity are risk factors for the disease.There are many complications in patients with this disease,which mainly involve multiple systems such as the circulatory system,nervous system,and endocrine system.2.Deficiency of both qi and yin with blood stasis,deficiency of liver and kidney with yin and blood stasis,and deficiency of yin and yang with blood stasis are the three most common syndrome types in patients with T2 DM and CHD.Syndrome is the main factor.In the process of treatment,both qi and nourishing yin should be emphasized,and blood circulation and blood stasis should be promoted.3.The patient’s age,course of diabetes,BMI,GLU,diabetic retinopathy and other factors have a certain correlation with T2 DM combined with CHD.
Keywords/Search Tags:Type 2 diabetes, Coronary Heart Disease, TCM syndrome type, Logistic regression analysis
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