New Anthropometric Indices To Identify New Onset Left Ventricular Hypertrophy Among Hypertensive Community Population

Objective: The main research aim is to evaluate the associations of body roundness index(BRI)and body adiposity index(BAI)with new onset left ventricular hypertrophy(LVH)over a 4-year period in a population in southern China.And to determine whether the new anthropometric indices could better predict LVH than the traditional ones.Methods: This was a retrospective cohort study.The study investigated 825 subjects with normal left ventricular mass index(LVMI)at baseline echocardiographic assessment and a readable echocardiogram at the end of 4-years follow-up.Anthropometric indices including body mass index(BMI),wait circumference(WC),waist-to-height ratio(WHt R),BRI,BAI were investigated.The associations between anthropometric indices and new onset LVH were evaluated by multivariate logistic regression.Receiver operating characteristic curves(ROC)and area under curve(AUC)were employed to compare the validity of each anthropometric index.Subgroup analysis was further conducted to evaluate the effects of age and sex on the associations of anthropometric indices and incident LVH.Results: Overall,51.3% of participates were female and the median of age was 62.2,over a period of 4 years,211 subjects(78.7% female,median age 64.6)occurred new onset LVH.In the multivariate logistic regression,after adjusted for potential confounders,all anthropometric indices were independent predictors of LVH.According to ROC analysis,BAI had the highest AUC for new onset LVH(AUC: 0.661,95CI%: 0.619-0.702).Conclusion: The study demonstrated that BMI,WC,WHt R,BRI,BAI were independently associated with new onset LVH and BAI was the best anthropometric index for detecting it.The correlation between BAI and new-onset LVH was consistent in both male and female subgroups.