Peripheral Blood Neutrophils/Lymphocyte Ratio And Platelet/Lymphocyte Ratio Affect The Prognosis Of Patients With Cerebral Infarction

Objective Inflammatory response participates in the whole process of developing acute cerebral infarction.Neutrophils/lymphocytes ratio and platelet/lymphocyte ratio is the new clinical markers of inflammation,reflect the body’s inflammatory state,can be used to predict the occurrence,development and prognosis of many kinds of disease of heart head blood-vessel.At present domestic about NLR and PLR less study on the prognosis of patients with cerebral infarction,therefore the purpose of this paper is to analyze NLR and PLR prognosis in patients with cerebral infarction.Methods Collect the 136 patients who diagnosed as acute cerebral infarction from first hospital affiliated to jinan university in April 2014 to April 2018.Input patients information by using Standardized questionnaire which including gender,age,medical history,past medical history,personal history,family history,Vital signs on admission,Completed auxiliary examination,etc.Patients can be divided into groups(good prognosis and poor prognosis group)by using Modified Rankin Scale(modified Rankin Scale,m Rs).Respectively on two groups of patients with gender,age,past medical history,NIHSS score(National Institute of Health Stroke Scale),clinical data and such as of 24 test indexes.Using binary logistic regression analysis and ROC(receiver operating charateristic curve,ROC)to evaluate the assessed value of This model for the prognosis of patients with acute cerebral infarctionResults(1)Good prognosis group include 79 cases,accounting for 58.1%;Poor prognosis group include 57 cases,accounting for 41.9%.Group compared with poor prognosis group by average shows:the difference in Diabetes,atrial fibrillation,NIHSS on admission,APOA,APOB,CRP,WBC,neutral particle counting,have statistical meaning(P<0.05).Binary logistic Regression analysis shows that:NIHSS score on admission(P=0.000)、APOB(P=0.003)、NLR(P=0.032)have positive influence on prognosis of patients who positive influence on prognosis of relationship.They are independent risk factors for prognosis of patients with acute cerebral infarction.(2)The area under the curve of ROC(NIHSS score on admission、APOB、NLR)is0.826(95%CI:0.756-0.895).Conclusion(1)NLR is independent risk factor for poor prognosis in patients with acute cerebral infarction,cannot think of PLR is independent risk factor for poor prognosis in patients with acute cerebral infarction.(2)NIHSS score on admission,APOB are independent risk factors for prognosis of patients with acute cerebral infarction.