Modulation Of Visual Perception By Brain Intervention On Primary Visual Cortex

The primary visual cortex is the first-level cortex of visual information processing,responsible for processing the information of visual stimuli,and is the simplest and earliest neural basis involved in perceptual organization activities.Non-invasive brain interventions in the primary visual cortex allow the study of causal links between the primary visual cortex and visual perception.Non-invasive transcranial magnetic stimulation and transcranial alternating current stimulation provides information on when and how areas of primary visual cortex are involved in cognitive processes offers the possibility in a frequency-specific manner to modulate brain oscillations associated with visual perception and to study their effects on different cognitive functions.However,there are still two unresolved problems in the modulation effect of brain intervention on primary visual cortex on visual perception,one is the influence of transcranial magnetic stimulation intervention parameters on the modulation effect,and the other is the neural mechanism of 10 Hz transcranial alternating current stimulation.This paper attempts to answer the above two questions through meta-analysis,brain intervention combined with electroencephalography.This article firstly conducted a meta-analysis of the literature on transcranial magnetic stimulation intervention in the primary visual cortex,and explored the modulation effects of different intervention factors on visual perception.Results showed that transcranial magnetic stimulation inhibited the perception of visual objects in most studies of visual perception,with effects that varied between studies and individuals.The meta-analysis found that major factors such as transcranial magnetic stimulation coil type,stimulation intensity,and the visual angle of the stimulis would affect the masking effect of transcranial magnetic stimulation to varying degrees,and transcranial magnetic stimulation had significant effects in multiple time windows.Further,the masking effect of single-pulse magnetic stimulation on visual perception in the classical time window was explored through the figure-background separation experiment,but the behavioral experimental results showed that the actual effect of transcranial magnetic stimulation did not meet expectations.Further,this paper explores the effect of alternating current stimulation on the primary visual cortex on the orientation discrimination task,and combines synchronized electroencephalography techniques to study the neural mechanism of this intervention effect.Results from behavioral data showed that the discrimination index and detection accuracy varied with the phase of transcranial alternating current stimulation,suggesting that transcranial alternating current stimulation may modulate target detection performance in a phase-dependent manner,highlighting the causal effect of alpha oscillations on visual perception effect.The results of the phase-phase coupling in the resting-state electroencephalography band show that the stimulation effect of 10 Hz ranscranial alternating current stimulation is not limited to the alpha band,but affects the self-coupling of the beta and gamma bands with higher frequencies,the results of restingstate brain network parameters suggest that the stimulating effect of transcranial alternating current is limited to the alpha frequency band.This paper studies the effect of a variety of transcranial magnetic stimulation intervention factors on visual perception through meta-analysis,which is helpful for follow-up research to determine what intervention methods to take.In addition,this paper explores the neural mechanism of the regulation of brain activity by transcranial alternating current stimulation through the experiment of transcranial alternating current stimulation combined with synchronized electroencephalography.