Analysis Of Risk Factors And Syndrome Elements In High-risk Stroke Population With Carotid Intimal Thickening

The formation of cardiovascular and cerebrovascular diseases is closely related to atherosclerosis.Atherosclerosis has been identified as one of the culprits.The formation,growth and rupture of plaque formed the pathological basis of atherosclerosis.Previous studies have confirmed that the active control of low density lipoprotein cholesterol can significantly reduce atherosclerosis formation and control the development of course of disease,atherosclerosis outcomes such as cerebral infarction,myocardial infarction and reduced by at least more than 30 percent,but there are still more than two thirds of patients the disease has not been effectively ease,we still need for the formation of atherosclerosis,or hardening of the arteries,the etiology and pathologic process for exploration and research in order to further reduce the incidence of atherosclerosis rate,delay the disease process to improve the quality of life.Because of modern medicine in the prevention and treatment of carotid atherosclerosis has certain limitations,more and more patients hope that through the treatment of traditional Chinese medicine to achieve the purpose of disease prevention.Although the atherosclerosis research of TCM theory is not perfect,has not yet formed complete system of TCM syndrome differentiation,but there is still a need for further clinical samples,high quality,multi center clinical study,with real guide the clinical practice.This study completely according to the screening criteria of the State Planning Commission,for stroke risk factors,and older than people over the age of 40 to develop traditional Chinese medicine symptom observation table,lifestyle survey,body mass index and blood pressure determination,and including the examination of carotid artery ultrasound,a series of physical,chemical and laboratory indexes,to discuss the risk factors of carotid atherosclerotic plaques,and explore the distribution of TCM syndrome elements.Research methods:according to the State Planning Commission to develop stroke screening standard,by in stroke screening and prevention project base hospital organization and unified formulation clinical observation table,according to participate in the screening of personnel training,to meet the conditions and with stroke risk due to population sample screening,selection between February 5,2012 to 2013,in Fengtai District,Beijing Fengtai District Zuo health service center and the Beijing Fangzhuang health service center to participate in screening the high risk population of stroke in patients.A total of 5807 cases of patients with high risk of carotid artery intima thickening in patients with high risk of stroke.This study is a clinical cross sectional survey.Using EpiD3.1 software to establish database,SPSS 20.0 statistical data,factor analysis was used to find out the sample population carotid artery intimal thickening is common in patients with symptomatic factors,based on the opinions of experts,initially identified common factor(syndrome factor)and number of each common factor includes symptoms,statistics and the distribution characteristics of syndrome factors.Result:1.At high risk of stroke associated with carotid intima media thickness in patients with risk factors with age,smoking,lack of exercise and hypertension,diabetes,stroke,coronary heart disease and hypertension,cerebral stroke and family history of coronary heart disease were related.2.The risk of stroke in high-risk groups,with more than four risk factors that are prone to carotid intimal thickening,up to seven risk factors.The most common risk factors for carotid artery intimal thickening in high risk group were hypertension,dyslipidemia,diabetes,overweight,family history,smoking and less physical exercise.3.High risk of stroke patients with carotid artery intimal thickening in patients with the highest proportion of Qi deficiency.4.There were significant differences in Yin deficiency,Yang deficiency and blood stasis syndrome between the female and male patients with high risk of cerebral stroke with carotid artery intimal thickening.5.At high risk of stroke associated with carotid artery intima-media thickening in patients,the proportion of patients under the age of 60,the deficiency of Qi and hot syndrome and blood stasis syndrome than in patients over 60 years old,over the age of 60 patients with Yang deficiency ratio is higher than that of patients under the age of 60.6.At high risk of stroke associated with carotid intima media thickness in patients and in patients with history of stroke the Yang deficiency and phlegm dampness syndrome proportion to higher than patients without stroke;without a history of stroke patients with syndrome of fire heat ratio is higher than that of a history of stroke patients.The incidence of yin deficiency syndrome and phlegm dampness syndrome in high risk group of patients with high risk of carotid artery was significantly higher than that of patients without hypertension.Patients with high risk of stroke in patients with carotid artery intimal thickening in patients with diabetes,the incidence of hot syndrome was significantly higher than the patients with no history of diabetes.Conclusion:1.Hypertension,dyslipidemia,diabetes,overweight,family history,smoking and less physical exercise are the risk factors of carotid artery intimal thickening in high risk group of patients with stroke.2.The high risk of stroke patients with carotid artery intimal thickening is characterized by the virtual reality,the actual situation of inclusion.The deficiency of Qi deficiency,Yin deficiency,Yang deficiency,and marked with hot,phlegm dampness,blood stasis.Qi deficiency throughout the disease,sixty years old the following patients with Qi deficiency and blood stasis,Qi deficiency syndrome;more than sixty years old patients with Yang deficiency.3.High risk of stroke with carotid artery intima thickening of traditional Chinese medicine should be "Qi deficiency and blood stasis".