Construction Of Boronate Affinity Functionalized Materials For The Adsorption And Separation Of Luteolin

Luteolin（LTL）is a biomolecule with cis-diol in its structure.LTL widely exists in plants,vegetables and fruits,especially in waste peanut shells.LTL has a variety of pharmacological effects,such as anti-inflammatory,anti-cancer,anti-oxidation and so on.It also has a certain protective effect on human nerves.The high medical value of LTL makes its separation and extraction of great significance.Boronate affinity material is a functional material that can selectively separate and enrich cis-diol biomolecules.The boronate affinity method has the advantages of strong specific affinity,broad-spectrum selectivity,reversibility,fast binding and resolution.With the theme of adsorption and separation of LTL in solution,the boronate affinity technique was combined with Pickering emulsion,Metal-organic frameworks（MOFs）and magnetic nanoparticles to prepare Al₂O₃@MMA-BA,Ui O-66-BA and Fe₃O₄@FPBA MNPs.The physical and chemical properties of the three boronate affinity functional adsorbents were characterized by various methods,and their adsorption properties and mechanism for LTL were studied through various adsorption experiments.The main contents are as follows:（1）The Al₂O₃@MMA-BA boron affinity microspheres were prepared by Pickering emulsion polymerization with nanometer Al₂O₃as stabilizer for emulsion,and 3-amino phenyl boron acid was used as the functional monomer in emulsion,and were used for the adsorption remove of LTL.The physicochemical properties of Al₂O₃@MMA-BA microspheres were investigated by various characterization methods.The results indicated that nanometer Al₂O₃ can stabilize Pickering emulsion well,and Al₂O₃@MMA-BA microspheres have a larger specific surface area and good thermal stability.The maximum adsorption capacity calculated by Langmuir model reached 18.736mg/g when the p H is 8.5 and the temperature is 45℃.Moreover,Al₂O₃@MMA-BA microspheres have a good regeneration capacity.（2）The boronate affinity functionalized Ui O-66-BA was prepared by introducing 4-carboxyphenyboronic（CPBA）acid as a functional component through the metal ligand fragment coassembly（MLFC）strategy.The framework crystallinity and LTL adsorption properties of the MOFs with different molar ratios of CPBA/1,4-dicarboxybenzene（BDC）were studied.The results showed that when the molar proportion of CPBA was greater than30%of the total molarity of CPBA/BDC,the frame crystallinity and the BET specific surface area of the Ui O-66-BA adsorbent were reduced.The adsorption performance and the regeneration performance of the Ui O-66-BA were poor.The addition of an appropriate amount of CPBA（≤30%）was conducive to the Ui O-66-BA to maintain a good crystal structure.The adsorption performance and regenerative capacity of the MOFs were improved.Among them,the equilibrium adsorption capacity of Ui O-66-BA-2 reached 42.509 mg/g when p H=8.5 and the temperature was 35℃.（3）The ammonia-modified magnetic nanoparticles（Fe₃O₄@NH₂ MNPs）were prepared by solvent thermal method,and then 4-formylphenylboric acid（4-FPBA）was introduced to prepare the boronate affinity functionalized magnetic nanoparticles（Fe₃O₄@FPBA MNPs）.The physicochemical properties Fe₃O₄@FPBA MNPs were characterized by various characterization methods.The results showed that the prepared Fe₃O₄@FPBA MNPs had a good crystal structure as well as high saturation magnetization.The maximum adsorption capacity of Fe₃O₄@FPBA MNPs calculated by Langmuir model reached 47.628 mg/g when the p H is 8.5 and the temperature is 35℃.At the same time,Fe₃O₄@FPBA MNPs have excellent reusability.