Research And Preparation Of Functional Waterproof And Breathable Medical Dressing

Textile materials are closely related to our lives,and they play an important role in the medical field.With the continuous progress and development of technology in the medical field,the demand for medical textile materials in medical and health care institutions is increasing day by day,and the performance,technology and quality of medical textile materials have also put forward higher requirements.This project firstly uses plasma technology to prepare polyethylene（PE）waterproof and breathable film,on the basis of which electrostatic spinning technology is used to prepare polyvinyl alcohol（PVA）and polyethylene（PE）composite waterproof and breathable dressing,and then applies magnetron sputtering technology to coat silver（Ag）nanoparticles on the surface of quartz（Quartz）fabric,and after compounding with PVA/PE film,its application in the field of functional waterproof and breathable dressing is investigated.The application in the field of medical dressings is discussed.In this thesis,three main aspects of work were carried out:（1）Preparation of PE waterproof and breathable film: Using plasma technology,the surface of PE film was treated with air plasma.By varying the number of plasma treatments,different degrees of etching effects were formed on the PE film surface.The structural properties of the material were observed and analyzed by scanning electron microscopy（SEM）,Fourier transform infrared spectroscopy（FTIR）,thermogravimetry（TG）,and differential scanning calorimetry（DSC）.The changes in contact angle,air permeability,and water vapor transmission rate of PE after plasma treatment were also measured and analyzed;（2）Preparation of PVA/PE waterproof and breathable medical film: PVA/PE composite waterproof and breathable dressing was prepared by electrostatic spinning method using plasma-treated waterproof and breathable PE film as the substrate.Glutaraldehyde was subsequently applied to cross-link the composite samples to improve their water stability and mechanical properties.Meanwhile,the structural properties,water vapor transmission rate,air permeability,tensile strength and antibacterial properties of the composite dressing were analyzed,and the cytotoxicity of the composite samples was assessed using fibrillogenic cells to demonstrate the applicability of the prepared waterproof breathable dressing on wounds.（3）Preparation and application of Ag@quartz/PVA/PE functional dressing: Silver nanoparticles were coated on the surface of quartz fabric by magnetron sputtering technique,and the prepared Ag@quartz was compounded with PVA/PE to obtain Ag@quartz/PVA/PE to study its application in the field of bioassay.The results show that:（1）after plasma treatment,the water contact angle of PE film is reduced from 112.67 ° to 45 °,and the surface of PE film is changed from a hydrophobic to a hydrophilic state.The permeability is improved to 0.450 mm/s,and the water vapor transmission rate can be increased to 1419.788 g/m²? h.（2）The WVT of the composite PVA/PE waterproof breathable film is 238.292 g/m²? h,the permeability is 5.798 mm/s,and its infrared transmission rate is up to 70%.It also has suitable antibacterial properties and good cytocompatibility.（3）The prepared Ag@quartz/PVA/PE showed excellent enhancement performance with an enhancement factor of 3.4×10⁵,detection limit below 10^-8 M/L,and good signal reproducibility with a relative standard deviation（RSD）of 5.31%,and good signal stability with RSD of3.54%.By coupling Ag@quartz/PVA/PE with a portable Raman spectrometer to detect the urea concentration signal,the detection performance was excellent,and the accuracy was high.Conclusions:（1）The treated polyethylene film possesses permeability,but does not transmit liquid water.The improved performance of polyethylene film expands the application of waterproof and breathable polyethylene film in the pharmaceutical field.（2）Compared with traditional dressings such as nonwoven cotton,PVA/PE composite dressing has good cooling performance,improves waterproof and breathable properties,and enhances wound healing,which has great potential for wound dressing applications.（3）Ag@quartz/PVA/PE has good potential for application in the field of functional medical dressings as a waterproof and breathable material that can be used for bioassay.