Study On Preparation And Antibacterial Properties Of ZnO Microtubes-based Composite Materials

With the widespread use of antibiotics,multi-drug resistant bacteria continue to emerge iteratively,which poses a serious threat to human health.ZnO is a traditional inorganic photocatalytic antibacterial material that can effectively solve the problem of bacterial resistance and plays an important role in antibacterial,water purification,and air purification fields.However,the contradiction between nanotoxicity and large-size antimicrobial effect limits the further application of ZnO in the field of medical protection.In this paper,ZnO single-crystal microtubes were prepared based on optical vapor supersaturated precipitation(OVSP).We also constructed a highly efficient micron-scale antimicrobial material by compounding functional materials on ZnO microtubes’ surface via two processes: "drop spraying" and "in situ solvothermal method".Based on this,we realized the application of antimicrobial functional protective masks and flexible dressings.Compared with the pure ZnO antimicrobial agent,the band gap of ZnO/GO is reduced by about 0.03 e V,and the photoluminescence intensity is attenuated by 68%.The photogenerated electron-hole pair complexation efficiency was reduced and the photocatalytic antimicrobial activity was significantly improved.The inhibition effect of ZnO/GO on E.coli and S.aureus was investigated under different light environments,doses,and action times.The antibacterial properties of the material gradually increased as the wavelength of the light source approached the intrinsic absorption region of ZnO/GO,and the inhibition effect on E.coli and S.aureus reached nearly 100% when the dose was 14g/L.Then,ZnO/GO composite material and polypropylene(PP)were combined using a coating process to prepare a reusable ZnO/GO/PP air filter membrane with fast and efficient antibacterial activity.The membrane has significant hydrophobic differences in different regions,which improves the ability to aggregate bacteria while ensuring the filtration capacity of the membrane.The antibacterial protective facial mask prepared by using ZnO/GO/PP air filter membrane as a functional sandwich not only has a good filtration effect on PM2.5,but also has an interception capacity of nearly 100% for E.coli.The protective facial mask still has good mechanical flexibility and structural stability under highfrequency bending at 200 times/min and 300 cycles.Finally,the ZnO microtubes were compounded and modified by a zeolite imidazole framework(ZIF)with high biocompatibility to generate in situ ZnO/ZIF-11 heterostructures,in which the ZIF-11 micron crystal size was about 10μm.The band gap of ZnO/ZIF-11 was reduced by 0.04 e V,and the photoluminescence intensity was attenuated by 83% compared with the pure ZnO antimicrobial agent.The intrinsic antibacterial efficiency was 89% and 98% for E.coli and S.aureus,respectively.On this basis,a flexible dressing with antimicrobial function was prepared by combining polydimethylsiloxane(PDMS)with ZnO/ZIF-11 composite,which exhibited excellent mechanical flexibility,stability and antibacterial ability and is expected to provide a material basis for antimicrobial work in human tissues.This paper provides new ideas for designing large-size antimicrobial materials,filter membranes and flexible dressings with high antimicrobial activity.