| Purpose:By mild cognitive dysfunction in type 2 diabetes in TCM research,in ginseng and astragalus educational refreshing treatment of mild cognitive dysfunction in type 2 diabetes kidney essence loss,phlegm and blood stasis resistance network syndrome patients.Reference for TCM syndrome integral,blood glucose(FBG,PBG,HbA1c),blood lipid(TG,TC,LDL-C)scale,Chinese simple mental state examination(MMSE)and the Chinese version of the Montreal cognitive assessment scale(MoCA)total score reduction etc index,to evaluate the effect of ginseng and astragalus educational refreshing party,security,and to explore its mechanism of action,for mild cognitive dysfunction in type 2 diabetes treatment of traditional Chinese medicine to provide evidence to support.Method:Mild cognitive dysfunction in type 2 diabetes,according to the syndrome types of disease diagnosis standard,will correspond to the two deficiency qi and Yin,phlegm and blood stasis of collaterals card card type choose out of the 60 cases of patients,the patients were randomly divided into 2 groups.The control group 30 cases,foundation treatment,namely sand Merformin Hydrochloride+Onglyza)+ nim horizon(nim)treatment,as well as other symptomatic treatment.Treatment group is in the control group treatment to ginseng and astragalus educational refreshing on the basis of treatment,the number is 30 cases,observation for 12 weeks.Observe two groups before and after treatment of clinical symptoms,blood glucose,blood lipid,cognitive function assessment scale and liver and kidney function changes of the efficacy index and safety index.Results:Through statistical software analysis,before the treatment,two groups of patients with basic data such as gender,age,course of no significant difference(P>0.05).(1)the clinical curative effect:after treatment of clinical curative effect of treatment group total effectiveness 90.00%,control group total effectiveness 66.67%,treatment group total effective rate was significantly better than that of control group(P<0.05).(2)syndromes curative effect:the treatment group after treatment of TCM syndrome curative effect,total effective rate 93.30%in the control group total effectiveness 66.67%,suggests that the treatment group on the improvement of the TCM syndrome significantly better than that of control group(P<0.05).(3)the blood sugar level:two groups after treatment in patients with FBG,PBG,HbAlc compared with before treatment were significantly decreased(P<0.05);Comparison between groups,the treatment group on blood sugar control effect is better than the control group(P<0.01).(4)lipid levels:treatment after comparison between the two way,TG,TC,LDL-C three levels have fallen,but particularly the TC drops,the P values<0.01,with statistical significance.So you can think,the treatment group on the control effect of TC is better than the control group.(5)the MoCA scale:the two groups after treatment in patients with MoCA rating scale from improved(P<0.05).Comparison between the two way,MoCA scale score improved significantly(P<0.01).(6)MMSE scale:the two groups after treatment in patients with MMSE scale score changes with statistical significance(P<0.05).The rating scale is compared between group make money have improved(P<0.05).(7)Safety indicators:ginseng and astragalus educational refreshing party in the treatment of mild cognitive dysfunction in type 2 diabetes mellitus with security,through the before and after treatment of blood in the urine stool routine,liver and kidney function of statistical analysis,there was no significant difference(P>0.05),and does not appear during treatment patients nausea and vomiting,dizziness,skin rash and other adverse reactions.Conclusion:After the clinical studies show that ginseng and astragalus educational refreshing party in the treatment of mild cognitive dysfunction in type 2 diabetes has significant curative effect,not only greatly improve the clinical symptoms of patients with the disease,but also can regulate blood sugar,improve the cognitive function and play a lipid-lowering effect.Through in the efficacy and safety of ginseng and astragalus educational refreshing party to observe,think this Fang Anquan valid... |
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