Pathogenic Bacteria Distribution And Drug Resistance Of Abdominal Aortic Aneurysm-related Infections

Objective: To understand the distribution of pathogens and drug resistance of abdominal aortic aneurysm-related infections and provide guidance for the clinical application of antibiotic therapy.Methods: The clinical data of patients with abdominal aortic aneurysm diagnosed in our hospital from December 2010 to December 2017 were collected in the study.Retrospective analysis was performed on patients with positive results of bacterial culture,drug sensitivity test and bacterial smear.Results: A total of 40 cases of abdominal aortic aneurysm-related infections,including nosocomial infections in 23 cases,8 cases of infected abdominal aortic aneurysm,vascular grafts infections(artificial vascular infection in 5 cases,2 cases of endovascular graft infection infection)in 7 cases,other Infections(incision infection in 1 case,community-acquired infection in 1 case)in 2 cases.There were 68 pathogens,25 Gram-positive bacteria(36.76%),36 Gram-negative bacteria(52.94%)and 7 fungi(10.29%).There were 42 pathogenic bacteria,14(33.33%)Gram-positive bacteria,21(50.00%)Gram-negative bacteria and 7(16.67%)fungi in nosocomial infections.Among them,Acinetobacter baumannii,The Gram-negative bacteria represented by this method showed high resistance to ampicillin,aztreonam,ciprofloxacin,ceftriaxone,cefepime,gentamicin,imipenem,levofloxacin and nitrofurantoin ≥91.67%,the low rate of levofloxacin,cotrimoxazole,tigecycline was less than or equal to 58.33%,Gram-positive bacteria represented by Staphylococcus aureus whose drug resistence rate of linezolid,tigecycline,teicoplanin,Vancomycin is 0;infected abdominal aortic aneurysm isolated 10 strains of Gram-positive bacteria 3(30.00%),Gram-negative bacteria 7 Strain(70.00%),13 pathogenic bacteria were isolated from vascular grafts infections,6(46.15%)Gram-positive bacteria and 7(53.85%)Gram-negative bacteria.Conclusions: The pathogens of abdominal aortic aneurysm-related infection are widely distributed and the proportion of pathogenic bacteria is different.Antibiotic therapy should be combined with experience-based treatment and susceptibility testing.Antibiotic therapy should be selected based on susceptibility results.