Effect Of Ultrasound-Guided Serratus Plane Block On Efficacy Of Postoperative Analgesia In Patients Undergoing Video-Assisted Thoracoscopic Surgery

Objective: To investigate the effect of ultrasound-guided serratus plane block on efficacy of postoperative analgesia in patients undergoing video-assisted thoracoscopic surgery.Methods: Sixty patients scheduled for video-assisted thoracoscopic radical resection of lung cancer under general anesthesia were randomly divided into two groups: SAPB group(experimental group,n=30)and control group(n=30),after induction of anesthesia,ultrasound-guided homolateral SAPB were performed,and 0.5% ropivacaine 20 ml was injected in group SAPB,while the equal volume of normal saline was used instead in control group.The patients received intravenous analgesia after operation in the two groups.The scores of visual analogue scale(VAS)and bruggrmann comfort scale(BCS)were evaluated at 1,2,4,6,12,24 and 48 h after operation.The consumption of additional pain medication within 48 h after operation,remifentanil were recorded.The adverse effects were also recorded.Results: The scores of VAS at postoperative 1h [(2.70±0.92)scores vs.(5.10±2.04)scores],2h [(2.80±1.00)scores vs.(5.13±1.78)scores],4 h [(3.07±1.17)scores vs.(4.93±1.53)scores],8h [(3.13±1.07)scores vs.(4.63±1.47)scores],12 h [(2.87±0.73)scores vs.(3.83±1.29)scores],the scores of BCS at postoperative 1h [(1.90±0.66)scores vs.(0.93±0.91)scores],2h[(2.03±0.41)scores vs.(0.90±0.80)scores],4h[(1.90±0.40)scores vs.(1.07±0.69)scores],8h[(1.97±0.32)scores vs.(1.20±0.66)scores],12h[(2.03±0.18)scores vs.(1.73±0.45)scores],remifentanil [(0.23±0.03)mg vs.(0.34±0.03)mg] and the consumption of additional pain medication within 48 h [(26.67±25.37)mg vs.(40.00±24.21)mg] were significantly lower in group SAPB than in control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion:The SAPB can reduce the early pain after video-assisted thoracoscopic radical resection of lung cancer,improve the comfort of patients,enhance the effect of postoperative analgesia and reduce the use of postoperative analgesic drugs.