| Objective: Through the retrospective comparative analysis of the clinical data of patients with tick-borne encephalitis(TBE)and Alongshan fever,this paper studies the differences between the two diseases,so as to provide a basis for their differential diagnosis.Methods: The case data of 135 cases of tick-borne encephalitis and 40 cases of Alongshan fever diagnosed in hospital at Inner Mongolia Forestry General Hospital(Second Clinical Medical College of Inner Mongolia University for Nationalities)between April 2017 and September 2021 were collected,and their epidemiological characteristics,clinical manifestations,auxiliary examinations,treatment and follow-up were retrospectively summarized and comparatively analyzed.Results: Statistically significant indicators in both groups were: 1.High fever was predominant in the tick-borne encephalitis group and low fever in the Alongshan fever group;2.Fever and loss of appetite were more common in the tick-borne encephalitis group and chest tightness was more common in the Alongshan fever group;3.Tick-borne encephalitis group was more prone to consciousness disorder,limb paralysis,muscle weakness,meningeal irritation and respiratory failure;4.In the tick-borne encephalitis group,an increase in blood count and eosinophilia were more common;5.Alongshan fever formation appears γ-Glutamyl transpeptidase(γ-The proportion of glutamyl transferase,GGT)increased was significantly higher;6.The tick-borne encephalitis group was more likely to have elevated C-reactive protein(CRP)and calcitonin(PCT);7.The cerebrospinal fluid(CSF)pressure was higher in tick-borne encephalitis group and more likely to have increased CSF white blood cell count;8.There are differences in EEG between the two;9.Patients with tick-borne encephalitis group have longer hospital stays;10.Tick-borne encephalitis group has a greater likelihood of leaving sequelae.Conclusions: 1.Epidemiological features: there is no significant difference between tick-borne encephalitis and Alongshan fever;2.Clinical manifestations: tick-borne encephalitis is more likely to have fever,and high fever is predominant,while Alongshan fever is predominantly low fever;symptoms of neurological damage are more common in tick-borne encephalitis;3.Ancillary tests: blood routine abnormalities and CSF abnormalities are more common in tick-borne encephalitis;liver damage is seen in both,but Alongshan fever fever is more likely to have elevated GGT;both have elevated inflammatory markers,but elevated CRP and PCT are more common in tick-borne encephalitis;EEG abnormalities are more common in tick-borne encephalitis;4.Treatment status: patients with tick-borne encephalitis have longer hospital stays;5.Follow-up status:tick-borne encephalitis is more likely to leave sequelae.In conclusion,tick-borne encephalitis is a relatively severe disease with frequent symptoms of neurological damage,a high rate of abnormalities in ancillary tests,and a relatively poor long-term prognosis;Alongshan fever is a relatively mild disease with rare symptoms of neurological damage,a low rate of abnormalities in ancillary tests,and a relatively good long-term prognosis. |