Study On The Relationship Between Red Blood Cell Count In Cerebrospinal Fluid And Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Objective To analyze the relationship between the number of red blood cells in cerebrospinal fluid(CSF)and cerebral vasospasm(CVS)after aneurysmal subarachnoid hemorrhage(ASAH)and to guide the treatment.Methods A retrospective study of medical data was conducted in 205 ASAH patients hospitalized in Shandong Provincial Qianfoshan Hospital from 2018.09 to 2021.09.According to the occurrence of CVS after operation,the patients were divided into two groups:CVS group and non-CVS group.The relationship between the basic condition at admission,the results of laboratory examination,imaging examination,aneurysm treatment and cerebral vasospasm were analyzed.Analyze the risk factors of CVS in patients with ASAH using single factor analysis and multiple factors logistic regression analysis.Results A total of 205 subjects were included,of which 59 cases developed cerebral vasospasm after operation.Single factor analysis showed that the number of red blood cells in cerebrospinal fluid was significantly correlated with CVS(P<0.001).After adjustment for age,Hunt-Hess scale and GCS score,multiple factors logistic regression analysis showed that the number of red blood cells in cerebrospinal fluid was significantly correlated with CVS(P<0.001).Conclusion The number of red blood cells in cerebrospinal fluid is an independent risk factor for CVS after ASAH,indicating that lumbar puncture or lumbar cistern drainage and other measures to reduce the number of red blood cells in cerebrospinal fluid may be effective methods to prevent CVS.