Clinical Study On Treatment Of Knee Osteoarthritis By Fired Needle Based On "Fired Paralysis" Theory

Objective To observe the clinical effect of internal heat acupuncture on knee osteoarthritis with cold and dampness obstruction,to seek a better plan for knee osteoarthritis with cold and dampness obstruction,and to provide a new idea for acupuncture treatment of the disease.Methods A total of 96 patients with knee osteoarthritis diagnosed with cold and dampness obstruction were randomly divided into internal heat acupuncture group(observation group),warm acupuncture group(control group A)and celecoxib group(control group B),with 32 cases in each group.They were admitted to the Department of Orthopedics and Trauma,Fuzhou Hospital of Traditional Chinese Medicine affiliated to Fujian University of Chinese Medicine from February 2021 to January 2022.Internal heat acupuncture group was treated once a week,warm acupuncture group was treated once every other day,celecoxib group was treated once a day,all three groups were treated for 4 weeks as a course of treatment,a total of 1course of treatment.VAS score,WOMAC score,TCM syndrome score,knee joint activity,serum TNF-α,IL-6,IL-1β content and infrared thermal imaging temperature were observed before and after treatment.Results 1.There was no statistical significance in VAS score,WOMAC score,TCM syndrome score,knee joint activity,serum TNF-α,IL-6 and IL-1β contents and infrared thermal imaging temperature before treatment among the three groups(P>0.05),and there was comparability among the three groups.2.Comparison of VAS scores: there were statistically significant differences in VAS scores between the three groups after treatment and before treatment(P < 0.05).After treatment,VAS score of internal heat acupuncture group was significantly different from celecoxib group or warm acupuncture group(P<0.05).There was no significant difference between celecoxib group and warm acupuncture group(P>0.05).3.Comparison of WOMAC score: There were statistically significant differences in WOMAC score between the three groups after treatment and before treatment(P < 0.05).After treatment,the WOMAC score of internal heat acupuncture group was significantly different from that of celecoxib group or warm acupuncture group(P < 0.05).There was no significant difference between celecoxib group and warm acupuncture group(P>0.05).4.Comparison of TCM syndrome score: there were statistically significant differences in TCM syndrome score between the three groups after treatment and the group before treatment(P<0.05).After treatment,the TCM syndrome score of internal heat acupuncture group was significantly different from that of celecoxib group or warm acupuncture group(P<0.05).There was no significant difference between celecoxib group and warm acupuncture group(P>0.05).5.Comparison of knee motion: there were statistically significant differences in knee motion between the three groups after treatment and the group before treatment(P < 0.05).After treatment,the knee motion of internal heat acupuncture group was significantly different from that of celecoxib group or warm acupuncture group(P < 0.05).There was no significant difference between celecoxib group and warm acupuncture group(P>0.05).6.Comparison of serum TNF-α,IL-6 and IL-1 β contents: There were statistically significant differences in serum TNF-α,IL-6 and IL-1β contents between the three groups after treatment and before treatment(P<0.05).After treatment,the contents of TNF-α,IL-6and IL-1 β in serum of internal heat acupuncture group were significantly different from those of celecoxib group or warm acupuncture group(P<0.05).There was no significant difference between celecoxib group and warm acupuncture group(P>0.05).7.Comparison of infrared thermal imaging temperature: the average temperature ofanterior,medial and lateral knee joint of the affected side in the three groups after treatment was statistically significant compared with that before treatment(P<0.05).After treatment,the mean temperature of anterior,medial and lateral knee joint of the affected side of internal heat acupuncture group was significantly different from that of celecoxib group or warm acupuncture group(P<0.05).There was no significant difference between celecoxib group and warm acupuncture group(P>0.05).Conclusions 1.The three treatment methods of internal heat acupuncture,warm acupuncture andcelecoxib have good clinical efficacy in improving the clinical symptoms,knee motionand inflammatory response of patients with knee osteoarthritis withcold and wet obstruction.2.Internal heat acupuncture is better than warm acupuncture or celecoxib in thetreatment of knee osteoarthritis with cold and dampness obstruction.