| Objective:Based on the orthogonal design experiment to study the three factors of myotonia in the motor dysfunction of Parkinson’s disease patients treated by acupuncture and moxibustion with the method of“Tiaoshen changzhi”(selecting acupoints,stimulating manipulation and moxibustion method),for each factor,two levels were selected(the acupuncture points were selected to regulate the mind and Changzhi 369 and the conventional acupuncture points,the stimulating techniques were selected to regulate the mind and perform acupuncture and the method of smoothing,reinforcing and reducing,and the MOXIBUSTION methods were selected to treat the DU channel heat-sensitive moxibustion and DU channel moxibustion),the clinical trial was arranged by orthogonal design method,and the optimized scheme of“Regulating mind and unblocking chi”acupuncture and moxibustion treatment for myotonia of Parkinson’s disease was obtained.Methods:The L4(2~3)orthogonal table was chosen according to the etiology and pathogenesis of myotonia in Parkinson’s disease and the Operability of the experiment.60 patients with myotonia of Parkinson’s disease were randomly divided into four groups,each group was treated with basic Western medicine,each group was treated with orthogonal design test,and each group was treated with acupoint selection(A),stimulating manipulation(B),moxibustion method(C)three factors and corresponding two levels of treatment,each treatment group received treatment for 12 weeks,the changes of UPDRS-III score(the motor function test part of Parkinson Unified Rating Scale),total score of Parkinsonian myotonia,modified Parkinsonian muscle tone rating scale(TAS,and functional disorder score of tremor syndrome were observed before and after treatment,and carry on statistical range analysis and variance analysis to the data obtained,to determine the significant factors affecting the changes of myotonia in Parkinson’s disease,and to determine the advantages and disadvantages of each factor at each level and the best treatment plan.Results:1.After 6 and 12 weeks of treatment with acupuncture and moxibustion,the UPDRS-III score,the Parkinsonian myotonia score,the Parkinsonian myotonia score and the functional disorder score of tremor syndrome of TCM were decreased in all groups,there was significant difference between before and after treatment(p<0.05).2.In the first 6 weeks and 12 weeks of treatment,the effect of the points selected in the Parkinson unified scale on motor function was greater than that of the points selected in the control group,the combination of A1b1c1(Tiaoshen Changzhi 369 acupoint selection,Tiaoshen Xingzhen acupuncture,du meridian heat-sensitive moxibustion)can improve the motor function of patients with myotonia of Parkinson’s disease most obviously.According to the total score of myotonia of Parkinson’s disease,the primary and secondary relationship of influencing factors in the whole process was as follows:selecting acupoints>stimulating manipulation>MOXIBUSTION method,and selecting acupoints was the most obvious factor affecting the score of myotonia,in the first 6 and 12 weeks of treatment,the combination of A1B1C1 was the most effective in improving myotonic symptoms of Parkinson’s disease.According to the TAS muscle tone score,the A1B1C1 combination was most effective in improving muscle tone in Parkinson patients during the first 6 weeks and the first 12 weeks of treatment.In the first 6 weeks and the first 12 weeks of treatment,the A1B1C1 combination had the best effect on improving the motor symptoms of Parkinson’s patients.Conclusion:The main influencing factor of acupuncture treatment on myotonic symptoms of Parkinson’s disease is to select acupoints,and the application of Tiaoshen Changzhi 369selection acupoints in early treatment has a better effect on improving myotonic symptoms of patients.Next is the stimulation technique,the stimulation technique chooses the mind-regulating walking acupuncture method to be more suitable.Finally,the MOXIBUSTION method,choose du meridian heat-sensitive moxibustion on the treatment of myotonia of Parkinson’s disease better effect.The Best Therapeutic Scheme of acupuncture and moxibustion for myotonia of Parkinson’s disease is Tiaoshen Changzhi 369 acupoint selection+Tiaoshen xingzhen needling+du meridian heat-sensitive moxibustion. |