| Objective:Through the retrospective analysis of hospitalized cases of atrial fibrillation（AF）in Inner Mongolia People’s Hospital,to understand the basic data,related risk factors and current treatment status of patients with AF in Inner Mongolia People’s Hospital.In order to further improve the proportion of standardized treatment of AF,so as to improve the prognosis and quality of life of patients,and at the same time fill in the gaps for the epidemiological data of AF in our district.Method:To collect the medical records of AF patients hospitalized in Inner Mongolia People’s Hospital from January 2019 to December 2020,including general condition,AF type,concomitant disease,laboratory index,bleeding and ischemia score,treatment plan etc.,and collated,statistically analyzed and summarized.Result:（1）A total of 2892 inpatients with AF were collected,including 1577 males and1315 females,with a male-to-female ratio of 1.2:1.The average age was 71.52±10.91.There were 12 patients in the<35-year-old group,accounting for 0.4%,179 patients in the 35-55 age group,accounting for 6.2%,1450 patients in the 55-75 age group,accounting for 50.1%and 1251 patients in the 75-year-old group,accounting for43.3%.1020 cases（35.3%）smoked,564 cases（19.5%）drank alcohol,and 312 cases（10.8%）were obese.There were 1010 patients with paroxysmal AF（30.9%）,1646patients with persistent AF（56.9%）and 236 patients with permanent AF（8.2%）.There were 307 patients with valvular AF,including 214 rheumatic heart valvular diseases,93 senile valvular diseases,accounting for 10.6%,and non-valvular AF 2585cases,accounting for 89.4%.Complicated with Coronary heart disease（CHD）,hypertension,diabetes,heart failure,cardiogenic stroke（cerebral artery embolism caused by AF in this study,hereafter referred to as stroke）,cardiomyopathy,hyperthyroidism,hypothyroidism and Chronic obstructive pulmonary disease（COPD）accounted for 37.21%,55.19%,19.99%,33.85%,16.15%,4.43%,2.83%,5.19%and12.76%,respectively.（2）AF was divided into paroxysmal,persistent and permanent groups according to duration.The three types of AF were associated with hypertension,heart failure,stroke,cardiomyopathy,thyroid disease and COPD,as well as ejection fraction,serum uric acid,low-density lipoprotein cholesterol（LDL-C）,N-terminal pro-B type natriuretic peptide（NT-Pro BNP）and C-reactive protein（CRP）were statistically significant（P<0.05）.According to the etiology,AF was divided into valvular AF and non-valvular AF.There was significant difference in gender composition,but there was no significant difference in the incidence of stroke.（3）There were 2585 patients with non-valvular AF and 418 patients with stroke.Univariate analysis showed that age,smoking,obesity,hypertension and diabetes had significant effects on non-valvular stroke.Taking stroke as dependent variable and statistically significant single factor as independent variable,binary logistic regression analysis showed that age（OR=1.081,95%CI 1.008-1.029,P=0.001）,obesity（OR=1.755,95%CI 1.155-2.668,P=0.008）,hypertension（OR=1.430,95%CI1.142-1.792,P=0.002）and diabetes（OR=1.330,95%CI 1.038-1.705,P=0.024）were risk factors of non-valvular AF stroke.（4）Stroke occurred in 4 cases in low-risk group,2329 cases in high-risk group,1826 cases in low-risk group and 1066 cases in high-risk group according to CHA2DS2-VASc score.（5）In 2310 non-valvular patients without stroke before starting medication,347patients took warfarin and the incidence of stroke was 18.7%,854 cases took rivaroxaban and the incidence of stroke was 8.3%,160 patients took dabigatran etexilate and the incidence of stroke was 3.8%.There were 949 patients without medication and the incidence of stroke was 19.9%.The incidence of stroke was different between different anticoagulant groups（P<0.05）.（6）The number and anticoagulant rate of AF patients in each department were1307 cases in cardiovascular department and the anticoagulant rate was 80.1%,309cases in emergency department and the anticoagulant rate was 67.3%,39 cases of cardiac surgery and the anticoagulation rate was 56.4%,355 cases in the department of neurology and the anticoagulant rate was 58.6%,35 cases in the department of critical medicine and the anticoagulant rate was 60.6%.There were 341 cases in other departments and the anticoagulation rate was 49.9%.（7）1697 cases were treated with beta blockers,559 cases with digitalis,24 cases with Shensong Yangxin capsule and 37 cases with Wenxin granule.289 were treated with amiodarone and 186 were cardioversion,34 patients took propafenone and 23received cardioversion,246 patients were treated with radiofrequency ablation and198 were cardiovered.The results showed that the conversion rate between propafenone,amiodarone and radiofrequency ablation was statistically significant（P<0.05）.And paroxysmal,persistent and permanent AF had statistical significance in the choice ofβ-blockers,digitalis,amiodarone and radiofrequency ablation.Conclusion:（1）55.04%of the patients with atrial fibrillation in our hospital are more than 65years old,indicating that atrial fibrillation is closely related to the increase of age.At the same time,the prevalence rates of hypertension and diabetes in patients with atrial fibrillation in our hospital are higher,which may be related to the eating habits,living environment and climate in Inner Mongolia.（2）The prevalence of permanent atrial fibrillation with hypertension,heart failure and stroke is significantly higher than that of paroxysmal and persistent atrial fibrillation,so active control of basic diseases is very important to delay the progress of atrial fibrillation.（3）The anticoagulant rate of atrial fibrillation in our hospital was 51.6%,and the overall anticoagulant rate of cardiology was 80.1%.Age,obesity,hypertension and diabetes were the risk factors of stroke with non-valvular atrial fibrillation and the incidence of stroke with new oral anticoagulants was significantly lower than that of warfarin.（4）The implementation of radiofrequency ablation in our hospital shows an upward trend and the conversion rate is high. |
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