Effect Of Pedicled Greater Omentum Embedding On Anastomosis Of Different Parts In Thoracoscopic Radical Esophagectomy

Objective: Pedicled greater omentum embedding is an important autologous tissue transplantation technology to prevent anastomotic leakage(AL)after radical resection of esophageal cancer,but the research evidence of its clinical treatment effect is still insufficient.Therefore,this study evaluated the effect of pedicled greater omentum embedding in the treatment of esophageal cancer.Methods: All patients with esophageal cancer who went to XX Hospital and underwent surgery from September 1,2016 to September 1,2021 were screened in strict accordance with the inclusion and exclusion criteria.The patients were divided into groups according to the location of gastroesophageal anastomosis,whether to accept pedicled greater omentum embedding and whether al occurred after operation.The perioperative clinical data of patients were extracted,and SPSS 22.0 was used for data entry and statistical analysis(test level)α=0.05),to evaluate the therapeutic effect of pedicled greater omentum embedding in the treatment of esophageal cancer.Results:Finally,a total of 246 patients were participated in this study.In the positive anastomotic leakage group,there were 8 cases in the chest anastomotic control group,7 cases in the chest anastomotic observation group,10 cases in the neck anastomotic control group and 8 cases in the neck anastomotic observation group.In the negative anastomotic leakage group,there were 61 cases in the chest anastomotic control group,65 cases in the chest anastomotic observation group,45cases in the neck anastomotic control group and 42 cases in the neck anastomotic observation group.In patients with postoperative AL,there were significant differences between the control group and the observation group in postoperative drainage volume,healing time of AL,and inflammatory indexes(CRP,PCT,IL-6)on the 3rd,5th and 7th day after operation in the chest anastomosis group or neck anastomosis group(P<0.05).In patients without postoperative AL,there were significant differences between the control group and the observation group in postoperative drainage volume,postoperative discharge time,inflammatory indexes (CRP,PCT,IL-6)at 3,5 and 7 days after operation in the chest anastomosis group or neck anastomosis group(P<0.05).Conclusion: Although the single center retrospective study has not found that pedicled greater omentum embedding can reduce the risk of anastomotic leakage,it can effectively reduce postoperative drainage,reduce postoperative inflammatory reaction and shorten hospital stay.For patients with AL,this operation can shorten the healing time of AL and help patients recover.