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In Fluencing Factors Of Efficacy And Safety Analysis Of Percutaneous Balloon Compression In The Treatment Of Trigeminal Neuralgia

Posted on:2023-12-26Degree:MasterType:Thesis
Country:ChinaCandidate:L JiangFull Text:PDF
GTID:2544306902985029Subject:Surgery (Neurosurgery)
Abstract/Summary:PDF Full Text Request
ObjectivesTrageminal neuralgia(TN)is one of the most common cranial nerve diseases.Percutaneous Balloon Compression(PBC)has become an important treatment for TN.The purpose of this study was to investigate the relationship between the postoperative efficacy of PBC in the treatment of TN and previous treatment and other related influencing factors,as well as the perioperative safety of TN patients with heart disease.The clinical data of TN patients were retrospectively analyzed.MethodsIn the first part,402 patients with primary trigeminal neuralgia(PTN)treated with PBC in our department from June 2019 to March 2021 were selected.According to the results of PBC treatment,they were divided into two groups:pain group and no pain group.The clinical correlation factors between the pain-free group and the pain-free group at 12 months after PBC were compared and analyzed.Data analysis was performed using R(http://www.r-projection.org)and Empower(R)(www.empowerstats.com,X&Y solutions,Inc Boston,MA,USA).Univariate analysis was performed to determine the correlation between variables such as age,sex,type of previous treatment,pain side,duration,distribution of pain,and postoperative facial numbness and the efficacy of percutaneous balloon compression(PBC)for PTN.In addition,multiple logistic regression models were used to evaluate the relationship between previous treatment and the outcome of this PBC treatment.In the second part,109 patients with primary trigeminal neuralgia treated with PBC in our department during the above period were selected,and the patients were divided into normal group and group with heart disease according to whether there was a concomitant heart disease,and the patients were divided into a decreased heart rate group and a non-decreased heart rate group according to whether there was a decreased heart rate and other changes during the operation.SPSS 24.0 statistical software was used to analyze the data,compare the clinical data of the two groups of patients,and compare the clinical efficacy,complications and perioperative safety of patients with heart disease and other related issues.Results1.402 TN patients were treated with PBC,of which 364 remained painless during the 12-month follow-up period.The type of previous treatment is closely related to the prognosis of PBC.The history of preoperative trigeminal radiofrequency(radiofrequency thermocoagulation,RF)plus gamma knife(gamma knife,GK)treatment is a risk factor for the prognosis of PBC.The type of preoperative treatment for PBC may be a predictor of poor surgical outcome.2.There was no significant difference in pain relief rate between the normal group and the group with heart disease at 6 months after operation.The incidence of decreased operative center rate in patients with heart disease was significantly higher than that in normal patients.Comparing the clinical data of patients in the decreased heart rate group and the non-decreased heart rate group,it was found that the patients in the decreased heart rate group were significantly older than those in the non-decreased heart rate group,and the patients with heart disease accounted for the vast majority in the decreased heart rate group.Conlusions1.This study suggests that PBC is safe and effective in the treatment of TN.2.PBC can also achieve ideal results for all types of recurrent TN(except those with a history of radiofrequency plus gamma knife surgery).3.According to the results of our study,the previous history of radiofrequency plus gamma knife surgery is the reason for the high recurrence rate of trigeminal neuralgia after PBC.4.PBC remains reliable,safe,and effective in the treatment of TN patients with heart disease and in older patients with heart disease.5.For older patients with heart disease undergoing PBC surgery,heart rate drops are more likely to occur during surgery.
Keywords/Search Tags:Trigeminal neuralgia, Percutaneous puncture balloon compression, Efficacy, Influencing factors, Safety
PDF Full Text Request
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