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Dietary Behavior Guidance Can Help Improve Metabolic Indicators Of People With Metabolic Disorders

Posted on:2024-08-27Degree:MasterType:Thesis
Country:ChinaCandidate:Y LuFull Text:PDF
GTID:2544306908483694Subject:Endocrine and metabolic disease
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Objective:To explore the association between the eating behaviors of consumption of hot food,consumption of snacks and eating fast in Chinese adults and type 2 diabetes mellitus(T2DM),and on this basis,to further explore the effects of the dietary prescription combined with eating behavior intervention on metabolic disorder population’s weight,glycolipid,blood pressure and other metabolic indicators,and to provide a scientific basis for the prevention and treatment of obesity and related metabolic diseases.Methods:This study was divided into two parts.In the first part,344 T2DM patients and 696 non-T2DM patients were randomly selected from December 2020 to March 2022 using a convenient sampling method.A cross-sectional survey was conducted through online distributionn of structured questionnaires,and the contents of the questionnaire included gender,age,height,weight,familial history of T2 DM,various eating behaviors and the prevalence of T2 DM.Logistic regression analysis was used to explore the association between the eating behavior of Chinese adults and T2DM.In the second part,36 overweight/obese patients were randomly selected from June 2022 to December 2022.The patients were randomly divided into AB group and BA group by using a coin toss method,with 18 patients in each group.The trial was divided into two intervention stages,in which AB group received the simple dietary prescription intervention scheme(Scheme A)in the first stage,and after a 14-day elution period,patients received the dietary prescription combined with eating behavior intervention scheme(Scheme B)in the second stage.The intervention sequence of BA group was reversed.Finally,the patients in both groups who received the Scheme A were collectively referred to as the simple dietary prescription intervention group(Group A),and those who received the Scheme B were collectively referredto as the dietary prescription combined with eating behavior intervention group(Group B).The difference analysis was used to compare the changes of metabolic indicators between the two groups of patients before and after intervention.Results:1.Gender(odds ratio(OR)=2.255,95%confidence interval(CI):1.559-3.260,P<0.001),age(OR=1.091,95%CI:1.075-1.107,P<0.001),BMI(OR=1.23 8,95%CI:1.034-1.483,P=0.020),familial history of type 2 diabetes(OR=5.709,95%CI:3.963-8.224,P<0.001),consumption of hot food(OR=4.132,95%CI:2.899-5.888,P<0.001),consumption of snacks(OR=1.745,95%CI:1.222-2.492,P=0.002),and eating fast(OR=1.292,95%CI:1.048-1.591,P=0.016)were risk factors for T2DM.2.After 8 weeks of the dietary prescription combined with eating behavior intervention,the patient’s weight,BMI,body fat percentage,waist-hip ratio,fasting plasma glucose,2hour postprandial plasma glucose,hemoglobin Alc,fasting nsulin,homeostasis model assessment-insulin resistance,triglyceride,total cholesterol,low density lipoprotein cholesterol,blood uric acid,and blood pressure were lower than before the intervention,with significant differences(P<0.05);while high density lipoprotein cholesterol,blood urea nitrogen,creatinine,and C-peptide increased compared to before the intervention,with significant differences(P<0.05).3.The attainment rate of weight,hemoglobin A1c,homeostasis model assessmentinsulin resistance,blood uric acid,blood lipids and blood pressure of patients and patients’compliance with dietary prescriptions in the dietary prescription combined with eating behavior intervention group was all higher than those in the simple dietary prescription intervention group.The difference between the two groups was statistically significant(P<0.05).Conclusion:Gender,age,BMI,familial history of T2 DM,consumption of hot food,consumption of snacks and eating fast are the risk factors of T2 DM.The dietary prescription combined with eating behavior intervention scheme can effectively reduce the weight of people with metabolic disorders,improve their glycolipid metabolism indexes,reduce blood uric acid and blood pressure,and significantly improve the compliance of patients with poor dietary control with dietary prescriptions,and the improvement effect is significantly better than that of the simple dietary prescription intervention scheme.
Keywords/Search Tags:Obesity, Type 2 diabetes mellitus, Eating behavior, Hedonic overeating
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