Study On Human Respiratory System Dynamics And Motion Numerical Simulation

Bronchoscopy plays a key role in the current treatment of lung diseases and it is typically an interventional medical instrument dominated by manual intervention.The current scientific study of bronchoscopy is essential to eliminate the problems associated with manual interventions,so research related to virtual surgery and automated interventions with instruments is essential.However,such research is not mature,and a method that can realistically and effectively simulate the tracheal deformation process during respiratory motion is urgently needed,so the study of tracheal deformation during respiratory motion is of great importance.First,based on anatomical and medical principles to analyze the forces of the respiratory system in the respiratory process,it was determined that the respiratory process was divided into two stages of exhalation and inhalation to consider.Analyzed the hydrostatic properties of the respiratory system and determine the solution of the trans-pulmonary pressure in the lungs.Analyzed the airway resistance and respiratory system kinetic characteristics in the expiratory and inspiratory phases of respiration,established a spring damping model,and obtained the respiratory mechanics model for each phase.The data of the input variables of the mechanics model were obtained,and the mechanics model was solved and fitted numerically using MATLAB to obtain the respiratory forces throughout the respiratory phase,and the results were compared with the literature to verify the accuracy of the model.Then,CT data from the open-source database were acquired to build a finite element model of the respiratory system,including the trachea,lungs,diaphragm and intercostal muscles,using Mimics.The numerical solution of the mechanical model was input to ABAQUS as external load for dynamics simulation,and the validity of the dynamics simulation was verified by comparing the simulated displacement data with literature data.The undeformed and maximally deformed trachea models were obtained from the simulation results,and the peak of the inlet velocity during breathing was selected as the boundary condition to perform Computational Fluid Dynamics(CFD)simulation on the trachea model.The results were compared to analyze the interaction between airflow and respiratory motion.Finally,MATLAB was applied to design the respiratory motion human-computer interaction platform,with functions including parametric calculation and fitting of respiratory mechanics model,ABAQUS respiratory motion dynamics simulation and operation of Unity 3D virtual platform.Determine how the dynamics simulation data was associated with the deformation of the trachea model within Unity 3D,and use 3D Max to orient the undeformed trachea model.Jointly Unity 3D constructed the virtual trachea model,calculated the deformation scaling factor of the virtual trachea model by simulating the displacement data,and applied the script drive to simulate the breathing motion.Interventional touch experiment using a force feedback device to verify the validity of a virtual tracheal model of respiratory motion.Experimentation of respiratory motion simulation using patients’ pulmonary function test data on the interactive platform and virtual trachea to verify the reliability of human respiratory system dynamics and motion simulation studies.The results show that the above study not only achieved parametric numerical simulation of human respiratory motion,but also achieved convenience and study scalability through human-computer interaction,which provides a certain basis for future research on virtual bronchoscopy.