| Objective:This thesis intends to observe the clinical efficacy of Ren-moxibustion in the treatment of Helicobacter pylori-associated gastritis associated with hepato-stomach discompatibility through randomized controlled clinical trials,enrich the treatment ideas and methods of the liver and stomach discompatibility syndrome of HPAG,and expand the range of diseases treated by Ren-moxibustion.Method:Following the principle of randomized control,66 patients who met the screening criteria were recruited from December 2021 to December 2022 and were divided into the treatment group and the control group,with 33 cases in each group.The treatment group was treated with Ren-moxibustion,while the control group was treated with quadruple therapy.The change of Hp value,eradication rate of Hp,score of TCM syndrome,and score of SF-36 were used as the observation indexes for a total of 1 course of treatment(4 weeks in the treatment group and 2 weeks in the control group).After the end of treatment,the score of TCM syndrome and the score of SF-36 were compared before and after treatment,and the Hp value and eradication rate were compared one month after the end of treatment,and the efficacy was evaluated.Results:In this study,61 cases were included,including 30 cases in the treatment group and 31 cases in the control group.(1)Comparison of general conditions:there was no statistical significance in the comparison of gender,age and course of disease between the two groups after analysis(P>0.05),and the baseline was comparable.(2)Comparison of total TCM syndrome scores between the two groups before and after treatment:Compared within the group,total TCM syndrome scores between the two groups before and after treatment was significantly better than that before treatment(P<0.01);Comparing the total scores of TCM syndromes between the two groups,the curative effect of the treatment group was significantly better than that of the control group(P<0.01).(3)Comparison of Hp values and eradication rate-between the two groups:Compared within the group,Hp values of the two groups were significantly reduced before and after treatment(P<0.01);The Hp value of the two groups after treatment was compared between the two groups,and the efficacy of the control group was better than that of the treatment group(P<0.05).The effect of control group was better than that of treatment group(P<0.05).(4)Comparison of(SF-36)between the two groups:Compared within the group,the scores of SF-36 in the two groups were increased before and after treatment(P<0.05);The six scores of(RP)、(BP)、(GH)、(VT)、(SF)and(RE)after treatment were compared between the two groups.The curative effect of the treatment group was better than that of the control group(P<0.05).There was no significant difference in(PF)、(MH)and(HT)scores(P>0.05).(5)The total effective rate of the two groups was 93.33%in the treatment group and 90.32%in the control group.The treatment group was higher than the control group,and the difference was not statistically significant(P>0.05).(6)The incidence of adverse reactions was compared between the two groups:6.67%in the treatment group and 19.35%in the control group,The treatment group was lower than the control group,and the difference was not statistically significant(P>0.05).Conclusion:The results of this study showed that both the Ren-moxibustion group and the conventional quadruplex group had good curative effects in the treatment of HPAG of liver and stomach disharmony type,and Ren-moxibustion had advantages in the improvement of TCM symptoms and quality of life,with small adverse reactions,high safety and comfortable treatment,which was worthy of clinical promotion and application. |
PDF Full Text Request