[Objective]The rapid recovery effect of BufeiHuoxue decoctionin on the patients in the perioperative period with non-small cell lung cancer who were diagnosed as deficiency of the lung and spleen,interjunction of phlegm and blood stasis.[Methods]Collected patients who were pathologically diagnosed as non-small-cell Lung Carcinoma from May 2018 to December 2019.The patients were randomly divided into treatment group and control group.42 cases in each group.For treatment group,Bufei Huoxue Decoction was given orally for one week during the perioperative period.Procalcitonin levels、c-reactive protein(CRP),IL-6(IL-6),tumor necrosis factor(TNF-α)and D-dimer(D-Dimer)were compared between the two group.Arterial blood gas indexes such as partial pressure of Oxygen(PaO2)and partial pressure of carbon dioxide(PaCO2).Coagulation indexes such as Prothrombin time(PT),duration of operation and amount of intraoperative bleeding,postoperative mechanical ventilation time,postoperative bed rest time,postoperative thoracic drainage fluid volume,postoperative drainage tube days,days in hospital,the incidence of postoperative complications such as infection,fever and dehiscence and the improvement of clinical symptoms on the 5th day after operation were compared between the two groups.[Results]1.Comparison of clinical efficacy:The total effective rate of the treatment group was 97.6%,higher than that of the control group 80.9%,P<0.05.2.Comparison of perioperative inflammatory indexes:Postoperative inflammatory indexes of all patients were increased to varying degrees,but the postoperative inflammatory indexes of patients in the treatment group were increased less than those in the control group,and recovered quickly.3.Comparison of postoperative complications and rehabilitation indexes:The amount of postoperative thoracic drainage fluid in the treatment group was less than that in the control group(286±38 VS 315±46,P=0.036).Postoperative bed time was shorter than control group(23.5±5.4 VS 27.3±6.5,P=0.013).The mean length of hospitalization was shorter than that of control group(7.07±1.1 VS 7.43±1.8,P=0.042).4.Comparison of perioperative arterial blood gas results:there was no statistical difference in preoperative PaO2 and PaCO2 levels between the two groups.The level of PaO2 on the first and third day after surgery was lower than that on the first day before surgery.The treatment group basically recovered to the level before surgery on the fifth day after surgery,but the control group was still lower than the level before surgery on the fifth day after surgery,P<0.05.Pairwise comparison of PaO2 levels at the same time after surgery showed that the treatment group was higher than the control group(97.7%VS 95.5%,P=0.027).5.There was no significant difference in PT value before and after treatment,operation duration and intraoperative blood loss between the two groups(P>0.05).[Conclusion]1.Bufei Huoxue decoction can reduce the inflammatory reaction,shorten the time of lying in bed and hospitalization,promote the recovery of lung function of the patients with non-small-cell Lung Carcinoma after Vats.2.Bufei Huoxue decoction does not increase the risk of perioperative bleeding.It is safe and worthy of promotion. |