| Objective:To observe the clinical effect of acupoint acupoint Tingi in the treatment of perennial allergic rhinitis(PAR)under the guidance of nasal endoscope,and to explore a new therapeutic method to improve the clinical therapeutic effect of PAR.Methods:A total of 112 PAR patients were recruited from the outpatient department of Otolaryngology,Xiyuan Hospital,China Academy of Chinese Medical Sciences from April 2020 to September 2021.PAR patients were randomly assigned to treatment group(56 cases)and control group(56 cases)by random number table method.The treatment group was treated with acupuncture at Biqiu acupoint under the guidance of nasal endoscope(twice a week),and the control group was treated with fluticasone propionate nasal spray(one spray per side,twice a day).The course of treatment in both groups was 3 weeks.General information(age,sex,course of disease,vital signs)of patients in both groups were recorded before treatment.The rhinitis main symptom score(TNSS),visual analog scale(VAS),nasal sign score and rhinoconjunctivitis quality of life questionnaire(RQLQ)score were observed to assess the changes in both groups before and after the treatment.The onset time and clinical efficacy of the two groups were evaluated after the course of treatment.The occurrence of adverse reactions during treatment was recorded to evaluate the safety of patients.Statistically,different statistical methods were used to analyze the data results,and the final analysis results are concluded.P<0.05 indicates that the difference is statistically significant.Results:1.After the treatment,a total of 5 patients in the two groups fell off,and a total of 107 patients finally completed the clinical study,including 55 in the treatment group and 52 in the control group.Before treatment,there were no significant differences in demographic characteristics,vital signs,disease course data,TNSS score,VAS score,nasal sign score and RQLQ score between the two groups(P>0.05),indicating that the two groups were comparable.2.TNSS score:After treatment,intra-group comparison showed that the TNSS single symptom score of nasal congestion,nasal itching,sneezing and runny nose and total TNSS score in the two groups were significantly lower than before treatment,and the differences were statistically significant after statistical analysis(P<0.05),indicating that both treatments were effective.Compared between groups,the treatment group was better than the control group in improving the TNSS score of nasal itching,sneezing and runny nose and total TNSS score(P<0.05),but there was no significant difference in nasal congestion(P>0.05).3.VAS score:After treatment,the VAS symptom scores overall nasal symptoms,nasal congestion,nasal itching,sneezing,runny nose and olfaction function in the two groups were significantly lower than those before treatment,and the difference was statistically significant(P<0.05).Compared between the two groups,the VAS scores of nasal symptoms,nasal itching,sneezing,runny nose and olfactory function in the treatment group were better than those in the control group(P<0.05),but there was no significant difference in nasal congestion(P>0.05).4.Nasal sign score:After treatment,nasal sign score of the two groups were significantly lower than before treatment,and the difference was statistically significant(P<0.05).Compared between the two groups,the treatment group and the control group had the same improvement effect on nasal signs,and the difference was not statistically significant(P>0.05).5.RQLQ score:After treatment,the RQLQ single score of activity,sleep,non-nasal/eye symptoms,practical problems,nasal symptoms,eye symptoms and emotionand and total RQLQ score in the two groups were significantly decreased after treatment compared with before treatment(P<0.05),indicating that the two groups had significant effects on the quality of life of PAR patients.After treatment,the RQLQ single score of activity,sleep,non-nasal/eye symptoms,practical problems,nasal symptoms,eye symptoms and emotionand and total RQLQ score in the treatment group were better than those in the control group(P<0.05).6.Onset time:After treatment,there was no significant difference in the onset time between the two groups after statistical analysis(P>0.05),indicating that the treatment group could achieve the same effect as the control group in terms of onset time.7.Clinical efficacy:After treatment,the total effective rate was 90.91%in the treatment group and 82.69%in the control group.There was no statistically significant difference between the two groups(P>0.05),indicating that the two treatments were effective in PAR patients but not significantly different,and the efficacy of the two groups was similar.8.Safety evaluation:During the treatment,7 patients in the treatment group had a small amount of nasal discharge with blood,which was stopped by themselves without special treatment.There were 2 patients in the control group who had headache after local spraying and withdrew from the experiment.Conclusion1.Acupuncture at Biqiu acupoint under the guidance of nasal endoscope and fluticasone propionate nasal spray are both effective in PAR patients,and their therapeutic levels are similar.2.Acupuncture at Biqiu acupoint under the guidance of nasal endoscope and fluticasone propionate nasal spray treatment can both improve the symptoms and signs of PAR patients,but the efficacy is better than fluticasone propionate nasal spray treatment in improving nasal itching,sneezing,runny nose and RQLQ score.3.There is no significant difference in the onset time of acupuncture at Biqiu acupoint under the guidance of nasal endoscope and fluticasone propionate nasal spray.4.Acupuncture at Biqiu acupoint under the guidance of nasal endoscope is safe and effective,which has the value of further research. |
PDF Full Text Request