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Randomized Controlled Clinical Study On Intervention Of Metabolic Syndrome With Integrated Traditional Chinese And Western Medicine Cardiac Rehabilitation Program

Posted on:2024-01-09Degree:MasterType:Thesis
Country:ChinaCandidate:J J LiFull Text:PDF
GTID:2544306923999489Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Objective:To observe the effect of integrated traditional Chinese and Western medicine cardiac rehabilitation program on waist circumference,cardiac metabolic parameters,cardiopulmonary function,and quality of life in patients with metabolic syndromeMethods:Using a randomized controlled study method,72 patients with metabolic syndrome who met the inclusion and exclusion criteria were divided into two groups,36 of whom were enrolled in the control group and maintained conventional Western medicine treatment for metabolic syndrome;Another 36 patients were enrolled in the intervention group(TC group),and were treated with a combined traditional Chinese and Western medicine cardiac rehabilitation program.The observation period was 3 months.Observe the waist circumference,body mass index(BMI),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C)levels,triglyceride levels(TG),serum total cholesterol levels(TC),fasting blood glucose levels(FPG),blood pressure(including systolic and diastolic blood pressure),Creactive protein(CRP),serum homocysteine levels(Hcy),and serum uric acid levels(UA)of the two groups before and after the intervention The maximum oxygen uptake(VO2MAX),6-minute walking test(6MWT),quality of life assessment scale(SF-36),self rating anxiety scale(SAS),and all data were analyzed using SPSS25.0 statistical software.Results:1.A total of 72 patients with metabolic syndrome who met the inclusion and expulsion criteria were included in the study,and 5 patients fell out.A total of 67 subjects completed the study,including 33 in the intervention group(TC group)and 34 in the control group.There was no statistically significant difference between the two groups in terms of gender,age,height,weight,basic disease history,and medication history,as well as observation indicators(P>0.05)2.Waist circumference:After 3 months of intervention,the waist circumference of TC group decreased compared to before intervention(P<0.05),and decreased compared to the control group after intervention(P<0.05);3.BMI index:After 3 months of intervention,BMI in TC group decreased compared to before intervention(P<0.05),and significantly decreased compared to the control group after intervention(P<0.001);4.Lipid level:After 3 months of intervention,low density lipoprotein(LDL-C),total cholesterol(TC),and triglycerides(TG)in the TC group decreased compared to before intervention,while high density lipoprotein cholesterol(HDL-C)increased compared to before intervention(P<0.05);Compared with the control group,triglyceride(TG)decreased,high-density lipoprotein cholesterol(HDL-C)increased(P<0.05),and low density lipoprotein(LDL-C)and total cholesterol(TC)showed no significant difference(P>0.05);5.Fasting blood glucose level:After 3 months of intervention,fasting blood glucose(FPG)in TC group decreased compared to before intervention(P<0.05),and decreased compared to the control group after intervention(P<0.05);6.Blood pressure:After 3 months of intervention,systolic blood pressure(SBP)in TC group decreased significantly compared to before intervention(P<0.001),and diastolic blood pressure(DBP)decreased compared to before intervention(P<0.05);Compared with the control group,systolic blood pressure(SBP)significantly decreased(P<0.001),and diastolic blood pressure(DBP)decreased(P<0.05);7.Secondary serological indicators:After 3 months of intervention,C-reactive protein(CRP),serum homocysteine(Hcy),and serum uric acid(UA)in TC group decreased compared with those before intervention(P<0.05);Serum homocysteine(Hcy)significantly decreased compared to the control group after intervention(P<0.001),while C-reactive protein(CRP)and blood uric acid(UA)did not differ significantly from the control group after intervention(P>0.05);8.Cardiopulmonary function and exercise tolerance:After 3 months of intervention,VO2MAX and 6MWT in TC group increased compared to before intervention(P<0.05);Compared with the control group,VO2MAX increased significantly(P<0.05),while 6MWT showed no significant difference(P>0.05);9.Quality of life and psychological status:After 3 months of intervention,the quality of life index(SF-36)in TC group significantly increased compared to before intervention(P<0.001),while the scores of self rating anxiety scale(SAS)and self rating depression scale(SDS)decreased compared to before intervention(P<0.05);The quality of life index(SF-36)significantly increased compared to the control group after intervention(P<0.001),while the scores of self rating anxiety scale(SAS)and self rating depression scale(SDS)decreased compared to the control group after intervention(P<0.05);10.Safety evaluation:During the entire intervention process,no adverse cardiovascular events occurred in both groups,and no sports injuries were found in TC group;11.Follow up:At the 6-month follow-up,the quality of life index(SF-36)in TC group significantly increased compared to before the intervention(P<0.001),while waist circumference,BMI,self rating anxiety scale(SAS)scores,and self rating depression scale(SDS)scores decreased compared to before the intervention(P<0.05);The quality of life index(SF-36)in the control group increased significantly compared to the follow-up period(P<0.001),while the waist circumference,BMI,self rating anxiety scale(SAS)scores,and self rating depression scale(SDS)scores in the control group decreased compared to the follow-up period(P<0.05);Conclusion:After 3 months of intervention with the integrated Chinese and Western medicine cardiac rehabilitation program in patients with metabolic syndrome,the patient’s waist circumference,body mass index,blood lipid level,fasting blood glucose,blood pressure,cardiopulmonary function,cardiopulmonary function,exercise endurance,quality of life,and psychological status were significantly improved.Our research shows that the integrated Chinese and Western medicine cardiac rehabilitation program can prevent the progress of cardiovascular diseases,effectively slow down the progress of metabolic syndrome,and has good safety.
Keywords/Search Tags:Integrated traditional Chinese and Western medicine, Heart rehabilitation, Metabolic syndrome, Randomly control, Clinical Research
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