Clinical Study Of Cervical LEEP And Pathological Margin After Cold Knife Conization

Objective: To analyze the clinical effects of two different operations on postoperative recovery of patients and pathological margins,and to analyze the pathological diagnosis results of patients undergoing Leep and cold-knife conical resection of the cervix for the first time.The effect of cervical coning surgery was evaluated by analyzing the pathological changes and the rate of residual lesions after the selection of individualized treatment after the initial coning.Methods: The treatment data of patients undergoing initial treatment in the department of gynecology of our hospital were collected,and the data of patients with cervical squamous intraepithelial tissue lesions were selected.According to the inclusion criteria,A total of 120 patients were selected and divided into two groups of 60 cases each.One group of patients was treated with cervical Leep surgery as group A,and the other group was treated with cold-knife conical resection as group B.Postoperative information of patients was collected after the surgery,and the positive rate of pathological return margin after the initial cervical Leep surgery and cold-knife conical resection,the diagnostic accuracy of preoperative and postoperative pathology,the amount of tissues removed after the surgery,the postoperative complications of patients,and the recurrence rate of postoperative cervical squamous intraepithelial lesions of patients were calculated.The factors related to postoperative residual lesions in the two groups were analyzed.Results:1.Comparison of the excised cervical tissue between the two groups: the average area of the excised cervical tissue in group A was 4.93±1.11cm~2,and the cone height was1.41±0.25cm;In group B,the average area of cervical tissue excised was 6.55±2.37cm~2,and the cone height was 1.65±0.39 cm.There were significant differences in cone area and cone height between the two groups(P<0.05).2.Comparison of postoperative complications between the two groups showed that there were 3 cases of postoperative bleeding and 4 cases of infection in group A,but there was no cervical adhesion.The overall complication rate of group A was 11.66%.Patients in group B had cervical adhesion in 1 case,infection in 3 cases,and bleeding in1 case.The overall incidence of postoperative complications in group B was 8.33%.There was no significant difference in the incidence of postoperative complications between the two groups.3.From the perspective of pathological consistency between the two groups,41 cases(68.33%)of patients in group A had the same preoperative and postoperative pathology,while 34 cases(56.66%)of patients in group B had the same preoperative and postoperative pathology.There was no significant difference in the consistency between the two groups.4.Comparison of the positive rate of pathological margins between the two groups showed that the positive rate of pathological margins in group A was positive in 2 cases(3.33%),and that in group B was positive in 0 cases(0.00%).There was no significant difference between the two groups.5.Comparison of the positive rate of pathological margins between the two groups showed that the positive rate of pathological margins in group A was positive in 2 cases(3.33%),and that in group B was positive in 0 cases(0.00%).There was no significant difference between the two groups.Conclusion:1.The clinical correlation analysis of cervical Leep and cold knife conization in the two groups showed that the diagnostic and therapeutic effects were very similar.However,the efficacy of Leep and cold-knife conization in the treatment of cervical intraepithelial lesions is similar in terms of the positive rate of incision margin,postoperative residual rate and recurrence rate,but the long-term recurrence rate of cold-knife conization is low.Therefore,cold-knife conization has important value in the diagnosis and treatment of a wide range of cervical lesions and early invasive cancer.2.Cervical Leep surgery for the treatment of the cervical cold knife cutting cone high level cervical intraepithelial lesions of postoperative hemorrhage,cervical stenosis,or adhesion,such as near future,low complication rate,less effect on the patients after birth,is worthy of clinical promotion method of treatment of cervical lesions,especially for for young patients want to retain reproductive function is very important.In addition,cervical Leep surgery is more simple and easy to operate,causing less pain to patients,and it is easier to be accepted by patients.