Analysis Of The Efficacy Of Fully Degradable Sinus Drug Stents And Budesonide Nasal Flush In The Surgical Treatment Of Chronic Rhinosinusitis

Objective The aim of this study was to analyse the differences in the efficacy of fully degradable sinus drug stents versus budesonide nasal flush in the surgical treatment of chronic sinusitis and to provide a clinical reference value for the precise treatment of chronic sinusitis.Methods From August 2020 to November 2022,60 patients with chronic sinusitis who had failed conservative treatment such as medication were selected to undergo functional nasal endoscopic surgery and fully degradable sinus drug stent implantation according to the patients’ own wishes,and were divided into two groups: experimental group(fully degradable sinus drug stent implantation group)and control group(budesonide flush group).There were no differences between the two groups in terms of preoperative age,gender,duration of disease,unilateral and bilateral,and eosinophil percentage at baseline,and no differences in the surgical and perioperative treatment protocols.All patients were followed up and examined one month and three months after surgery and completed The 22-item sino-nasal outcome test(SNOT-22)to assess patients’ postoperative quality of life and improvement in symptoms.A nasal endoscopy was also completed to look for the formation of vesicles or polyps in the operative cavity,the need for further intervention,adhesions,lateralisation of the middle turbinates and frontal sinus effusion.In addition,patients with combined asthma or allergic rhinitis were further analysed.Results The clinical symptoms of patients in both groups were significantly improved compared with those before surgery.One month after surgery: the SNOT-22 score was significantly lower in the experimental group than in the control group(P < 0.05),and three months after surgery: there was no statistical difference between the SNOT-22 scores of the two groups(P > 0.05).The postoperative nasal endoscopic findings of the two groups suggested that there was no significant difference in the remaining indicators(P > 0.05),except that the experimental group formed significantly fewer vesicles or polyps than the control group at one month postoperatively(P < 0.05).Patients with chronic sinusitis combined with asthma or allergic rhinitis in both groups benefited from the treatment.Postoperative nasal endoscopic findings in patients with chronic sinusitis combined with asthma or allergic rhinitis showed that frontal sinus effusion was significantly lower in the experimental group than in the control group(P< 0.05).Conclusion Both fully degradable sinus stenting and budesonide nasal flsuh are effective adjuncts in the surgical management of chronic sinusitis,with no statistically significant difference in their overall effectiveness.However,in patients with combined asthma or allergic rhinitis,fully degradable sinus stents were superior to budesonide nasal flush in improving drainage from the frontal sulcus.