| Objective: To investigate the predictive value of baseline urinary albumin/urinary creatinine(UACR)and N-terminal B-type natriuretic peptidogen(NT-pro BNP)in patients with heart failure with preserved ejection fraction(HFp EF)for the recurrence of heart failure hospitalization(HHF)events 3 months after hospital discharge.Methods: 227 patients with heart failure with preserved ejection fraction(HFp EF)hospitalized at the Third Affiliated Hospital of Anhui Medical University from January 2021 to March 2022 were enrolled,and baseline Urine albumin-to-creatinine ratio(UACR)and N-terminal pro-B-type natriuretic peptide(NT-pro BNP)were measured.patients were divided into the event group and control group according to whether they had a recurrence of Hospitalization for heart failure(HHF)events within3 months of discharge,and the differences between the two groups were compared to analyze the relationship with short-term heart failure readmission in patients with HFp EF.Results: Baseline levels of UACR and NT-pro BNP were higher in patients in the event group compared with the control group(P < 0.05).With increasing urinary albumin levels,there was a significant difference in NYHA heart classification,Ln NT-pro BNP and heart failure readmission in HFp EF patients(P < 0.05),with 50%of patients in the massive albuminuria group having HHF events 3 months after discharge.pearson correlation analysis revealed a positive correlation between Ln UACR and Ln NT-pro BNP(r = 0.463,P < 0.001).Multifactorial logistic regression showed that after correcting for age,systolic blood pressure,blood sodium,and ejection fraction,UACR(OR = 1.408,95% CI 1.037-1.911,P < 0.05)and NT-pro BNP(OR = 3.218,95% CI 2.028-5.105,P < 0.001)remained 3 months in HFp EF patients.Conclusion: UACR and NT-pro BNP are independent risk factors for HHF recurrence at 3 months in patients with HFp EF,and the combination of the two has a higher predictive value. |
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