| Objective: In this study,the distribution law of traditional Chinese medicine constitution in elderly hypertension patients was discussed,and the correlation between clinical characteristics and traditional Chinese medicine constitution was analyzed,so as to provide reference for the early prevention and intervention of traditional Chinese medicine in elderly hypertension patients.Methods: In this study,208 elderly patients with hypertension were selected from the outpatient department and inpatient department o f the First Affiliated Hospital of Heilongjiang Hospital of Traditional Chinese Medicine from November 2021 to December 2022.General conditions,disease information and clinical indicators of elderly hypertension patients were collected,and TCM physique of elderly hypertension patients was identified according to TCM Physique Classification Criteria.Observe the correlation between TCM constitution and influencing factors,and use SPSS software for statistical analysis of relevant data.Results:1.TCM constitution distribution of elderly hypertension patients has certain regularity,and the frequency of distribution is phlegm-dampness quality,Qi-deficiency quality,yang-deficiency quality,blood-stasis quality and qistagnation quality in order from high to low.2.There was statistical significance in the distribution of TCM constitution in elderly hypertension patients(P<0.05).The elderly hypertension patients with male,drinking history,overweight,hyperlipidemia and cerebrovascular diseases had more distribution in phlegm and dampness.Female patients with diabetes mellitus and hypertension grade 2 were more distributed in Yin deficiency.The distribution of blood stasis was more in the elderly patients aged 75-80 years and with grade 3 hypertension.The distribution of TCM constitution of elderly hypertension patients with disease course > 20 years was mainly Qi-deficiency;In the elderly patients with hypertension and heart failure,the distribution of Yang deficiency and phlegm-dampness was more.3.There were statistically significant differences in TC,LDL,TG,FBG and Cr among elderly hypertension patients with traditional Chinese medicine constitution(P<0.05).The TC level of phlegm-dampness group was significantly higher than that of non-phlegm-dampness group,and that of Yin deficiency group was higher than that of Yang deficiency group,blood stasis group and qi deficiency group.The level of LDL in phlegm-dampness group was significantly higher than that in non-phlegm-dampness group,and the level of TG in Qi-deficiency group was lower than that in evenness group.FBG in Yin deficiency group was significantly higher than that in phlegm dampness group,Pinghe group,blood stasis group and Qi stagnation group,while FBG in Yang deficiency group was higher than that in blood stasis group.The Cr of Yang deficiency group was significantly higher than that of Yin deficiency group and Pinghe group,and the Cr of phlegm-dampness group was higher than Pinghe group.4.The differences of carotid plaque and IMT distribution in elderly hypertension patients with different constitutions of traditional Chinese medicine had statistical significance(P<0.05).The plaque in the phlegm-dampness group of elderly hypertension patients was significantly higher than that in the non-phlegm-dampness group,and the IMT in the phlegm-dampness group was significantly higher than that in the Yin deficiency group,qi deficiency group,Yang deficiency group and qi stagnation group.5 Ambulatory blood pressure parameters5.1 The difference of d SBP,d DBP and n SBP in TCM constitution of elderly hypertension patients was statistically significant(P<0.05).The d SBP level of phlegm-dampness group was significantly higher than that of Yin deficiency,Yang deficiency and peace quality group.d DBP of Tan-dampness group was higher than that of Qi deficiency group,blood stasis group,qi stagnation group and Yang deficiency group.The level of n SBP in Yin deficiency group was higher than that in phlegm-dampness group,Pinghe group,Qi stagnation group and Yang deficiency group.5.2 The difference of d SBPV,24 h SBPV and 24 h DBPV of TCM constitution in elderly patients with hypertension was statistically significant(P<0.05),and d SBPV in Yin deficiency group was higher than that in phlegm-dampness group,Qi stagnation group and peace group;The 24 h SBPV of Yin deficiency group was higher than that of Qi deficiency group,Qi stagnation group and blood stasis group.24 h DBPV of Qi-deficiency group was lower than that of Pinghe group.5.3 The difference of TCM constitution n SCV and 24 h SCV in elderly hypertension patients was statistically significant(P<0.05),and the Yin deficiency group had higher n SCV than qi stagnation,phlegm-dampness,peace,qi deficiency and Yang deficiency groups.The 24 h SCV of Yin deficiency quality group was higher than that of phlegm-dampness quality,Pinghe quality,blood stasis quality,Qi deficiency quality and Qi stagnation quality group,and the 24 h SCV of Yang deficiency quality group was higher than that of Qi stagnation quality group.5.4 The difference of traditional Chinese medicine constitution in blood pressure circadian rhythm distribution of elderly hypertension patients was statistically significant(P<0.05).The distribution of non-arytenoid in phlegmdampness and Yin deficiency was greater than that in other constitutions,and the distribution of anti-arytenoid in qi deficiency was higher than that in nonqi deficiency.6.Logistic regression analysis showed that the general conditions of elderly hypertension patients were correlated with clinical indicators and different physical conditions,TC,LDL,IMT were positively correlated with phlegm-dampness quality,FBG,24 h SBPV,non-arytenoid type was positively correlated with Yin deficiency quality,disease course>20 years,inverse-arytenoid type curve was positively correlated with qi deficiency quality.Conclusion:1.The distribution of TCM constitutions in elderly hypertension patients is mainly phlegm-dampness,Yin deficiency and qi deficiency,suggesting that these three constitutions are the main susceptible constitutions of the disease.2.In elderly hypertensive patients,the phlegm-dampness quality is prone to dyslipidemia,IMT thickening and plaque formation,the Yin deficiency quality is prone to increased systolic blood pressure variability,non-arytenoid blood pressure and blood glucose abnormalities,and the qi deficiency quality is prone to reverse arytenoid blood pressure and long disease course.3.Logistic regression analysis showed that the main clinical characteristics of elderly hypertension patients were correlated with different constitutions.Target organ damage is more likely in elderly hypertension patients with phlegm-dampness and Yin deficiency,suggesting the significance of diag nosis and treatment. |
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