Clinical Observation Of Ultrasound Guided Paravertebral Nerve Block Combined With Lidocaine Gel Plaster In The Treatment Of Postherpetic Neuralgia

Objective To analyze the clinical efficacy and safety of ultrasound-guided paravertebral nerve block combined with lidocaine gel patch in the treatment of postherpetic neuralgia.Methods A total of 80 patients with thoracolumbar postherpetic neuralgia admitted to our hospital from October 2020 to December 2021 were selected and divided into control group and treatment group according to random number table method,with 40 cases in each group.The control group was treated with ultrasound-guided paravertebral block,and the treatment group was treated with ultrasound-guided paravertebral block combined with lidocaine gel plaster.The visual analog scale(VAS)score and Pittsburgh sleep quality Index(PSQI),the dosage of pregabalin and the incidence of adverse reactions were compared between the two groups before treatment(T0),1 week after treatment(T1),2 weeks after treatment(T2),3 weeks after treatment(T3),4 weeks after treatment(T4)and 8 weeks after treatment(T8).Results VAS scores of test groups at T1,T2,T3,T4 and T8 were(5.20±0.82)points,(3.90±0.77)points,(3.58±0.76)points,(2.62±0.69)points,(1.98±0.48)points,respectively.Compared with control group(6.03±1.07)points,(4.95±0.81)points,(4.03±0.83)points,(3.05±0.76)points,(2.55±0.50)points,all P <0.05.PSQI of the treatment group was significantly lower than that of the control group at the same time point,and the difference was statistically significant(ALL P<0.05).The effective rate of the treatment group was 77.5%,which was 50% better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Ultrasound-guided paravertebral nerve block combined with lidocaine gel patch can effectively relieve postherpetic neuralgia and improve sleep quality of patients with good safety.