| Objective: To evaluate the clinical efficacy and safety effect of Qipi Huashifang on abnormal glucose tolerance(IGT)in the prophase of diabetes mellitus with spleen deficiency and dampness retention.Methods: Sixty-six patients who met the inclusion and exclusion criteria were randomly divided into two groups,including 33 cases in the treatment group and 33 cases in the control group.The treatment cycle was 4 weeks.The changes of FPG,2h-PG,Hb A1 c,FINS and HOMA-IR before and after treatment and the symptoms evaluated by traditional Chinese medicine were recorded.Results:(1)The difference of FPG,2h-PG,FINS and HOMA-IR counts between the two groups before and after treatment was statistically significant,and the difference between the two groups before and after treatment showed that the treatment group was higher than the control group,with statistical significance.There was no statistical difference between the two groups after Hb A1 c treatment.(2)The results of comprehensive treatment with traditional Chinese medicine showed that the total effective rate of the treatment group was 87.88%,which was higher than that of the control group(66.67%),and the difference was statistically significant(P<0.05);(3)There were statistically significant differences in TCM symptom score between the two groups before and after treatment.The difference between the two groups before and after treatment showed that in the treatment group were significantly higher than those in the control group(P< 0.05).Conclusion:Qipi huashifang and eliminating stasis can effectively reduce the Blood sugar,improve Insulin resistance,and obviously improve the symptoms such as the body is heavy and weak,the diet is poor and the diarrhea and the mouth is tasteless or sticky.The efficacy of Qipi Huashifang and eliminating stasis indiabetes mellitus with spleen deficiency and dampness retention is better than that of Simple lifestyle intervention. |
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