Application Of Superb-micro-vacular Imaging In The Diagnosis Of Benign And Malignant Thyroid Nodules

Objective:This study aims to analyze the application value of ultra-microscopic blood flow imaging(SMI)in the diagnosis of benign and malignant thyroid nodules.Methods From January 2021 to December 2021,the ultrasound and pathological data of161 thyroid nodules from 143 patients with thyroid nodules were collected and classified according to the thyroid imaging porting and data system(TI-RADS)classification.The results were compared with the pathological results.The blood flow richness,blood flow distribution type and vascular morphology of benign and malignant thyroid nodules under SMI mode were analyzed;Results(1)The blood flow richness of 161 thyroid nodules under SMI mode was compared,and 84.5% of thyroid nodules were lack of blood supply;There was no significant difference between the two groups in the blood flow abundance of thyroid benign and malignant nodules(P>0.05).There was no significant difference in the blood flow abundance of thyroid benign and malignant nodules.(2)The blood vessel distribution types of benign and malignant nodules with poor blood supply were compared under SMI mode,and there was statistical significance between the two groups(P<0.05).(3)The blood vessel routing of benign and malignant thyroid nodules was analyzed in the SMI mode.and there was statistical significance between the two groups(P<0.05).87.5%of thyroid nodules pathologically confirmed as malignant have tortuous and irregular blood vessels.(4)Analyze and compare the blood flow detection of benign and malignant thyroid nodules in color Doppler flow imaging(CDFI)and SMI mode,and draw the ROC curve.The AUC of SMI mode(0.731,95CI: 0.624-0.838)is significantly higher than that of CDFI mode(0.649,95CI: 0.525-0.773).There is statistical significance between the two groups(P<0.05).(5)The univariate results showed that age,nodule nature,nodule location,size,internal echo of nodule,boundary between nodule and surrounding gland,nodule shape,degree of calcification and other univariate factors were compared between benign and malignant nodules,and there was statistical significance between the two groups(P<0.05).Conclusion: The distribution type of malignant nodules in thyroid nodules with poor blood supply is mainly peripheral vascular type;Malignant nodules mainly have tortuous and irregular blood vessels,while benign nodules have regular and uniform blood vessels;Thyroid nodules with abundant blood supply and peripheral radiating blood vessels or radiating from the inside to the periphery are typical features of malignant nodules;Nodules with abundant blood supply and circular or semi circular blood flow is a typical feature of benign nodules;SMI can more accurately detect the blood flow of nodules with different properties,and has high diagnostic efficacy in the diagnosis of benign and malignant thyroid nodules.