Objective: To observe the relevant indexes of Qingfei Tongfu Decoction in the treatment of community acquired pneumonia(phlegm-heat obstructing lung syndrome),and to preliminarily discuss the clinical efficacy of Qingfei Tongfu Decoction in the treatment of community acquired pneumonia(phlegm-heat obstructing lung syndrome)combined with statistical analysis of relevant data.Methods: The source of this clinical study was mainly 72 patients who were hospitalized in the Department of Respiratory and Critical Care Medicine(Pulmonary Department)of Kunming Hospital of Traditional Chinese Medicine from December 2021 to December2022.SPSS random table was used to divide them into treatment group and control group,36 cases in each group.The treatment period was 1 week.The control group was treated with conventional western medicine,and the treatment group was treated with Qingfei Tongfu decoction on the basis of the control group.In this clinical observation,the traditional Chinese medicine was decocted and sent to the ward by Kunming Hospital of Traditional Chinese Medicine,one dose per day,and taken twice in the morning and evening before meals.The TCM syndrome score,laboratory data(white blood cell,procalcitonin,C-reactive protein,neutrophil percentage,erythrocyte sedimentation rate,interleukin-6),the days of disappearance of clinical symptoms,hospitalization days and imaging manifestations of the two groups of patients before and after the clinical observation were observed and recorded in time.Results:1.General data: because 2 cases dropped out of the treatment group and 3 cases dropped out of the control group,there were 34 cases in the treatment group and 33 cases in the control group.There was no significant difference in gender,age and smoking history between the two groups before and after clinical treatment(P > 0.05).2.Laboratory data: there were no significant differences in white blood cell(WBC),procalcitonin(PCT),C-reactive protein(CRP),neutrophil percentage(NE%),erythrocyte sedimentation rate(ESR),interleukin-6(IL-6)and other laboratory data between the two groups before clinical treatment(P > 0.05).The laboratory indexes of the treatment group and the control group decreased after clinical treatment,and there were statistically significant differences between the two groups(P < 0.05).3.TCM syndrome score: there was no significant difference in TCM syndrome score between the two groups before clinical treatment(P > 0.05).The TCM syndrome scores of the treatment group and the control group decreased after clinical treatment,and the difference between the two groups was statistically significant(P < 0.05).4.Imaging findings: there was no significant difference in chest CT findings between the two groups before and after treatment(P > 0.05).5.The days of disappearance of clinical symptoms and length of hospital stay:the days of disappearance of clinical symptoms and length of hospital stay in the two groups were decreased,and there were significant differences between the two groups(P < 0.01).6.Safety evaluation: there was no significant difference in ALT,AST and urine Cr between the two groups before treatment(P > 0.05).After treatment,the values of the two groups decreased,with statistically significant differences(P< 0.05),and within the safe range.There were no adverse reactions in the two groups before and after clinical treatment,which met the safety requirements of clinical observation.Conclusion:Through this clinical observation,it can be found that Qingfei Tongfu Decoction combined with conventional Western medicine has obvious advantages in the treatment of community-acquired pneumonia(phlegm-heat obstructing lung syndrome)compared with single Western medicine treatment.Through its unique anti-inflammatory and bronchial smooth muscle relaxation effects,Qingfei Tongfu Decoction can safely relieve patients’ cough,phlegm and other clinical symptoms,and effectively shorten the length of hospital stay of patients.It also provides a new research idea and treatment direction for the treatment of community-acquired pneumonia by integrated Chinese and western medicine. |